Sleep disturbances (SD) accompany many neurodevelopmental disorders, suggesting SD is
a transdiagnostic process that can account for behavioral deficits and influence underlying …

Sleep is a ubiquitous and complex behavior in both its manifestation and regulation. Despite
its essential role in maintaining optimal performance, health, and well-being, the genetic …

The choroid plexus (ChP) in the brain ventricles has a major influence on brain
homeostasis. In this study, we aimed to determine whether the circadian clock located in …

In many childhood-onset genetic epilepsies, seizures are accompanied by neurobehavioral
impairments and motor disability. In the Stargazer mutant mouse, genetic disruptions of …

Abstract Study Objectives Sleep is an important biological process that is perturbed in
numerous diseases, and assessment of its substages currently requires implantation of …

The endogenous circadian period of animals and humans is typically very close to 24 h.
Individuals with much longer circadian periods have been observed, however, and in the …

Sleep latency, the amount of time that it takes an individual to fall asleep, is a key indicator of
sleep need. Sleep latency varies considerably both among and within species and is …

It is well established that the oldest chronotype questionnaire, the morningness-
eveningness questionnaire (MEQ), has significant heritability, and several associations have …

Abstract Study Objective Validate a novel method for sleep-wake staging in mice using
noninvasive electric field (EF) sensors. Methods Mice were implanted with …

Genome-wide association studies reveal many non-coding variants associated with
complex traits. However, model organism studies largely remain as an untapped resource …