3D printing in personalized drug delivery: An overview of hot-melt extrusion-based fused deposition modeling
Advancements in pharmaceutical technologies have led to the personalization of therapies
over the last decade. Three-dimensional printing (3DP) is an emerging technique in the …
over the last decade. Three-dimensional printing (3DP) is an emerging technique in the …
Hydroxypropyl methylcellulose acetate succinate as an exceptional polymer for amorphous solid dispersion formulations: A review from bench to clinic
A Butreddy - European Journal of Pharmaceutics and …, 2022 - Elsevier
Amorphous solid dispersions (ASDs) are a proven system for achieving a supersaturated
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …
[HTML][HTML] Recent advances in pharmaceutical cocrystals: From bench to market
The pharmacokinetics profile of active pharmaceutical ingredients (APIs) in the solid
pharmaceutical dosage forms is largely dependent on the solid-state characteristics of the …
pharmaceutical dosage forms is largely dependent on the solid-state characteristics of the …
Quality-by-design in hot melt extrusion based amorphous solid dispersions: An industrial perspective on product development
An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …
Design and optimization of ciprofloxacin hydrochloride biodegradable 3D printed ocular inserts: Full factorial design and in-vitro and ex-vivo evaluations: Part II
Coupling hot-melt extrusion (HME) with fused deposition modeling three-dimensional
printing (FDM-3DP) can facilitate the fabrication of tailored, patient-centered, and complex …
printing (FDM-3DP) can facilitate the fabrication of tailored, patient-centered, and complex …
Pharmaceutical Co-crystals, Salts, and Co-amorphous Systems: A novel opportunity of hot-melt extrusion
S Narala, D Nyavanandi, P Srinivasan… - Journal of drug delivery …, 2021 - Elsevier
Enhancing the solubility of active drug ingredients is a major challenge faced by scientists
and researchers. Different approaches have been explored for the enhancement of solubility …
and researchers. Different approaches have been explored for the enhancement of solubility …
Opportunities and challenges in mechanochemical cocrystallization toward scaled-up pharmaceutical manufacturing
Recently, pharmaceutical cocrystals have gained immense interest because of their
potential to tune mechanical, pharmacokinetic, and physicochemical properties of active …
potential to tune mechanical, pharmacokinetic, and physicochemical properties of active …
[HTML][HTML] Innovations in thermal processing: hot-melt extrusion and KinetiSol® dispersing
Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …
Creation of hydrochlorothiazide pharmaceutical cocrystals via hot-melt extrusion for enhanced solubility and permeability
Crystal engineering is an emerging tool for altering the physicochemical properties of drug
candidates. The objective of the current investigation was to develop cocrystals of …
candidates. The objective of the current investigation was to develop cocrystals of …
Melt crystallization of celecoxib-carbamazepine cocrystals with the synchronized release of drugs
A Chen, P Cai, M Luo, M Guo, T Cai - Pharmaceutical Research, 2023 - Springer
Purpose The fixed-dose combination drug products have been increasingly used to treat
some complex diseases. A cocrystal containing two therapeutic components, named as a …
some complex diseases. A cocrystal containing two therapeutic components, named as a …