Vascular disease in cocaine addiction

K Bachi, V Mani, D Jeyachandran, ZA Fayad… - Atherosclerosis, 2017 - Elsevier
Cocaine, a powerful vasoconstrictor, induces immune responses including cytokine
elevations. Chronic cocaine use is associated with functional brain impairments potentially …

Drug abuse and stroke

AC Fonseca, JM Ferro - Current neurology and neuroscience reports, 2013 - Springer
Cerebrovascular disorders contribute to the morbidity and disability associated with illicit
drug use. Drug abusers have an increased risk of both hemorrhagic and ischemic stroke. In …

Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014 - Am Heart Assoc
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Nephrotoxic effects of common and emerging drugs of abuse

WF Pendergraft III, LC Herlitz… - Clinical journal of the …, 2014 - journals.lww.com
The kidneys can be injured in diverse ways by many drugs, both legal and illegal. Novel
associations and descriptions of nephrotoxic effects of common and emerging drugs of …

Cardiovascular consequences of cocaine use

RV Stankowski, RA Kloner, SH Rezkalla - Trends in cardiovascular …, 2015 - Elsevier
The cardiovascular consequences of cocaine use are numerous and can be severe, with
mechanisms of cardiotoxicity unique to cocaine that include sympathomimetic effects …

Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings

HC Fox, D Seo, K Tuit, J Hansen… - Journal of …, 2012 - journals.sagepub.com
Cocaine dependence is associated with increased stress and drug cue-induced craving and
physiological arousal but decreased prefrontal activity to emotional and cognitive challenge …

[HTML][HTML] Hormonal and dietary characteristics in obese human subjects with and without food addiction

P Pedram, G Sun - Nutrients, 2014 - mdpi.com
The concept of food addiction (FA) is a potentially important contributing factor to the
development of obesity in the general population; however, little is known about the …

Influence of mitochondrion-toxic agents on the cardiovascular system

J Finsterer, P Ohnsorge - Regulatory Toxicology and Pharmacology, 2013 - Elsevier
Cardiovascular disease may be induced or worsened by mitochondrion-toxic agents.
Mitochondrion-toxic agents may be classified as those with or without a clinical effect, those …

Distinct inflammatory profiles in HIV-infected individuals under antiretroviral therapy using cannabis, cocaine or cannabis plus cocaine

FOF de Castro, JM Silva, GP Dorneles… - Aids, 2019 - journals.lww.com
Objectives: To evaluate the effects of cannabis and/or cocaine use on inflammatory,
oxidative stress status and circulating monocyte subsets in HIV-infected individuals under …

Cellular response of the blood-brain barrier to injury: potential biomarkers and therapeutic targets for brain regeneration

MM Tenreiro, R Ferreira, L Bernardino, MA Brito - Neurobiology of Disease, 2016 - Elsevier
Endothelial cells are the main component of the blood-brain barrier (BBB), a vital structure
for maintaining brain homeostasis that is seriously disrupted in various neurological …