Frailty and cancer: current perspectives on assessment and monitoring
V Goede - Clinical interventions in aging, 2023 - Taylor & Francis
Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …
Geriatric assessment and management in cancer
As the majority of patients with cancer are older than 65 years, most medical, surgical, and
radiation oncologists treat a large number of older adults in their clinical practice. Older …
radiation oncologists treat a large number of older adults in their clinical practice. Older …
Integrated Geriatric Assessment and Treatment Effectiveness (INTEGERATE) in older people with cancer starting systemic anticancer treatment in Australia: a …
Background The effectiveness of comprehensive geriatric assessment (CGA) in improving
health outcomes in cancer settings is unclear. We evaluated whether CGA can improve …
health outcomes in cancer settings is unclear. We evaluated whether CGA can improve …
Initial panitumumab plus fluorouracil, leucovorin, and oxaliplatin or plus fluorouracil and leucovorin in elderly patients with RAS and BRAF wild-type metastatic …
S Lonardi, C Rasola, R Lobefaro, D Rossini… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To verify whether both doublet chemotherapy with a modified schedule of
fluorouracil, leucovorin, and oxaliplatin (mFOLFOX) and monochemotherapy with …
fluorouracil, leucovorin, and oxaliplatin (mFOLFOX) and monochemotherapy with …
The use of immunotherapy in older patients with advanced non-small cell lung cancer
M Tagliamento, M Frelaut, C Baldini, M Naigeon… - Cancer Treatment …, 2022 - Elsevier
Immune checkpoint blockers (ICBs) have a pivotal role in the management of non-small cell
lung cancer (NSCLC), both as single agent and in combination strategies, providing a …
lung cancer (NSCLC), both as single agent and in combination strategies, providing a …
Cancer care for people with dementia: Literature overview and recommendations for practice and research
As many countries experience population aging, patients with cancer are becoming older
and have more preexisting comorbidities, which include prevalent, age‐related, chronic …
and have more preexisting comorbidities, which include prevalent, age‐related, chronic …
Frailty assessment in the care of older people with haematological malignancies
V Goede, NR Neuendorff, RJ Schulz… - The Lancet Healthy …, 2021 - thelancet.com
Frailty, defined as an age-related state of increased vulnerability to acute stressors, is a
major challenge in the care of older people with haematological malignancies. Growing …
major challenge in the care of older people with haematological malignancies. Growing …
Management of prostate cancer in older adults
LS Graham, JK Lin, DE Lage, ER Kessler… - American Society of …, 2023 - ascopubs.org
The majority of men with prostate cancer are diagnosed when they are older than 65 years;
however, clinical trial participants are disproportionately younger and more fit than the real …
however, clinical trial participants are disproportionately younger and more fit than the real …
The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review
Introduction Frailty is a complex multifactorial syndrome characterised by a significant
increase in vulnerability and worsened health outcomes. Despite a range of proposed frailty …
increase in vulnerability and worsened health outcomes. Despite a range of proposed frailty …
Frailty affects prognosis in patients with colorectal cancer: a systematic review and meta-analysis
M Cai, Z Gao, J Liao, Y Jiang, Y He - Frontiers in Oncology, 2022 - frontiersin.org
Background The prevalence of colorectal cancer has remained high. Most patients have
already developed into the middle and advanced stage when they are diagnosed with …
already developed into the middle and advanced stage when they are diagnosed with …