Ferroptosis as a mechanism of non-ferrous metal toxicity
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
Y Xie, AH Meijer, MJM Schaaf - Frontiers in cell and developmental …, 2021 - frontiersin.org
Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A
Cancer cells reprogram their copper metabolism to adapt to adverse microenvironments,
such as oxidative stress. The copper chelator elesclomol has been reported to have …
such as oxidative stress. The copper chelator elesclomol has been reported to have …
Structural characterization and anti-inflammatory activity of neutral polysaccharides from American ginseng
L Xie, H Yan, L Han, L Cui, H Hussain, Q Feng… - International Journal of …, 2023 - Elsevier
American ginseng, a precious classic herbal medicine, is used extensively in China for life
prolongation purpose. This study aimed to elucidate the structure and anti-inflammatory …
prolongation purpose. This study aimed to elucidate the structure and anti-inflammatory …
CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
T Cheng, Y Wu, Z Liu, Y Yu, S Sun, M Guo… - Frontiers in …, 2022 - frontiersin.org
Currently, breast cancer (BRCA) has become the most common cancer in the world, whose
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
Anti-Inflammatory and Antioxidant Properties of β-Sitosterol in Copper Sulfate-Induced Inflammation in Zebrafish (Danio rerio)
β-Sitosterol, which is used extensively in pharmaceuticals, nutraceuticals, and cosmetics,
has high nutritional value along with immunomodulatory and anti-inflammatory properties. In …
has high nutritional value along with immunomodulatory and anti-inflammatory properties. In …
1H-Pyrazole-4-carboxylic acid-based metal–organic frameworks: multifaceted materials
Abstract Metal-organic frameworks (MOFs), consisting of metal ions or clusters coordinated
with organic ligands, are a class of crystalline materials that have garnered widespread …
with organic ligands, are a class of crystalline materials that have garnered widespread …
Serum zinc, copper, and other biometals are associated with COVID-19 severity markers
The objective of the present study was to evaluate of serum metal levels in COVID-19
patients with different disease severity, and to investigate the independent association …
patients with different disease severity, and to investigate the independent association …
Hepatic transcriptomic and histopathological responses of common carp, Cyprinus carpio, to copper and microplastic exposure
SM Hoseini, K Khosraviani, FH Delavar… - Marine Pollution …, 2022 - Elsevier
The combined effects of copper and polyvinyl chloride (PVC) microparticles were
investigated on the metal accumulation, histopathological biomarkers, and targeted …
investigated on the metal accumulation, histopathological biomarkers, and targeted …
A tandem activation of NLRP3 inflammasome induced by copper oxide nanoparticles and dissolved copper ion in J774A. 1 macrophage
X Tao, X Wan, D Wu, E Song, Y Song - Journal of hazardous materials, 2021 - Elsevier
For the first time, we reported that CuONPs exposure induced interleukin (IL)− 1β-mediated
inflammation via NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) inflammasome …
inflammation via NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) inflammasome …