Asthma and allergy are common conditions with complex etiologies involving both genetic
and environmental contributions. Recent genome‐wide association studies (GWAS) and …

Asthma is a complex disease that results from the interaction between genetic predisposition
and environmental factors. Recently, genome-wide association studies have identified a …

Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …

The ratio of false-positive to false-negative findings (FP: FN ratio) is an informative metric
that warrants further evaluation. The FP: FN ratio varies greatly across different …

Transforming growth factor–β (TGFβ) is a multifunctional cytokine that plays diverse roles in
physiologic processes as well as human disease, including cancer, heart disease, and …

Allergic asthma is a chronic airway inflammatory disease in which exposure to allergens
causes intermittent attacks of breathlessness, airway hyper-reactivity, wheezing, and …

Consistent with the diversity of Latin America, there is profound variability in asthma burden
among and within countries in this region. Regional variation in asthma prevalence is likely …

Background Asthma is a complex disease with both genetic and environmental causes.
Genome-wide association studies of asthma have mostly involved European populations …

In utero smoke exposure has been shown to have detrimental effects on lung function and to
be associated with persistent wheezing and asthma in children. One potential mechanism of …

Asthma is the result of a complex interaction between environmental factors and genetic
variants that confer susceptibility. Studies of the genetics of asthma have previously been …