Homopharma: a new concept for exploring the molecular binding mechanisms and drug repurposing

YY Chiu, JH Tseng, KH Liu, CT Lin, KC Hsu, JM Yang - BMC genomics, 2014 - Springer
Background Drugs that simultaneously target multiple proteins often improve efficacy,
particularly in the treatment of complex diseases such as cancers and central nervous …

SARELI: Sequence Alignment by Radial Evaluation of Local Interactions

R Ortega, A Chavoya, C López-Martín… - Current …, 2018 - ingentaconnect.com
Background: A robust guide tree is necessary as a first step for the multiple sequence
alignment of proteins. The guide tree is normally generated using an initial distance matrix …

測定蛋白質模板中不連續片段之結構相似度

楊凱傑, 董其樺 - … of Information Technology and Applications (資訊 …, 2014 - airitilibrary.com
在目前結構比對領域中, 有許多研究者致力於開發高效率, 高準確性比對蛋白質的結構演算法,
但較少演算法可提供在空間中多個不連續片段的結構比對. 本論文針對此議題提出一個利用距離 …

Advances in translational bioinformatics and population genomics in the Asia-Pacific

S Ranganathan, S Tongsima, J Chan, TW Tan… - BMC genomics, 2012 - Springer
The theme of the 2012 International Conference on Bioinformatics (InCoB) in Bangkok,
Thailand was" From Biological Data to Knowledge to Technological Breakthroughs." …