Parkinson's disease (PD) is a chronic neurodegenerative condition affecting more than 1%
of people over 65 years old. It is characterized by the preferential degeneration of …

Protein aggregation, mitochondrial dysfunction, iron dyshomeostasis, increased oxidative
damage and inflammation are pathognomonic features of Parkinson's disease (PD) and …

This review provides an overview of the synaptic dysfunctions of neuronal circuits and
underlying neurochemical alterations observed in the hyperkinetic movement disorders …

Abstract Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder
emerging in early life characterized by impairments in social interaction, poor verbal and …

The heterotrimeric G-protein α subunit, Gα olf, acts to transduce extracellular signals through
G-protein coupled receptors (GPCRs) and stimulates adenylyl cyclase mediated production …

The neuronal isoform of nitric oxide synthase (nNOS) and its interacting protein NOS1AP
have been linked to several mental disorders including schizophrenia and depression. An …

Simple Summary Snake venoms are rich in molecules acting on different biological systems,
and they are responsible for the complications following snake bite envenoming. These …

Non-apoptotic caspase-3 activation is critically involved in dendritic spine loss and synaptic
dysfunction in Alzheimer's disease. It is, however, not known whether caspase-3 plays …

Striatal projection neurons, which are classified into two groups—direct and indirect pathway
neurons, play a pivotal role in our understanding of the brain's functionality. Conventional …

Spatial omics holds great potential to elucidate tissue architecture by dissecting underlying
cell niches and cellular interactions. However, we lack an end-to-end computational …