Alzheimer's pathogenic mechanisms and underlying sex difference
AD is a neurodegenerative disease, and its frequency is often reported to be higher for
women than men: almost two-thirds of patients with AD are women. One prevailing view is …
women than men: almost two-thirds of patients with AD are women. One prevailing view is …
[HTML][HTML] Sex differences in Alzheimer's disease: insights from the multiomics landscape
Alzheimer's disease (AD) has complex etiologies, and the impact of sex on AD varies over
the course of disease development. The literature provides some evidence of sex-specific …
the course of disease development. The literature provides some evidence of sex-specific …
Identification and immunological characterization of cuproptosis-related molecular clusters in Alzheimer's disease
Y Lai, C Lin, X Lin, L Wu, Y Zhao, F Lin - Frontiers in aging …, 2022 - frontiersin.org
Introduction Alzheimer's disease is the most common dementia with clinical and
pathological heterogeneity. Cuproptosis is a recently reported form of cell death, which …
pathological heterogeneity. Cuproptosis is a recently reported form of cell death, which …
Alzheimer's disease large-scale gene expression portrait identifies exercise as the top theoretical treatment
MA Hill, SC Gammie - Scientific reports, 2022 - nature.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects multiple
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …
Complement-mediated synapse loss in Alzheimer's disease: mechanisms and involvement of risk factors
L Wen, D Bi, Y Shen - Trends in Neurosciences, 2024 - cell.com
The complement system is increasingly recognized as a key player in the synapse loss and
cognitive impairments observed in Alzheimer's disease (AD). In particular, the process of …
cognitive impairments observed in Alzheimer's disease (AD). In particular, the process of …
Deep phenotyping of Alzheimer's disease leveraging electronic medical records identifies sex-specific clinical associations
AS Tang, T Oskotsky, S Havaldar, WG Mantyh… - Nature …, 2022 - nature.com
Alzheimer's Disease (AD) is a neurodegenerative disorder that is still not fully understood.
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
Sex difference in biological change and mechanism of Alzheimer's disease: From macro-to micro-landscape
SS Cui, QW Jiang, SD Chen - Ageing Research Reviews, 2023 - Elsevier
Highlights•AD disproportionally affects women in the development, progression and clinical
presentation of AD.•Our review summarized sex differences in biological change of AD from …
presentation of AD.•Our review summarized sex differences in biological change of AD from …
Distinct sex-specific DNA methylation differences in Alzheimer's disease
T C. Silva, W Zhang, JI Young, L Gomez… - Alzheimer's research & …, 2022 - Springer
Background Sex is increasingly recognized as a significant factor contributing to the
biological and clinical heterogeneity in AD. There is also growing evidence for the prominent …
biological and clinical heterogeneity in AD. There is also growing evidence for the prominent …
Expanding the scope of health disparities research in Alzheimer's disease and related dementias: Recommendations from the “Leveraging Existing Data and Analytic …
I Akushevich, J Kravchenko, A Yashkin… - Alzheimer's & …, 2023 - Wiley Online Library
Topics discussed at the “Leveraging Existing Data and Analytic Methods for Health
Disparities Research Related to Aging and Alzheimer's Disease and Related Dementias” …
Disparities Research Related to Aging and Alzheimer's Disease and Related Dementias” …
Do microbes play a role in Alzheimer's disease?
Alzheimer's disease is a complex and progressive condition that affects essential
neurological functions such as memory and reasoning. In the brain, neuronal loss, synaptic …
neurological functions such as memory and reasoning. In the brain, neuronal loss, synaptic …