High cortisol and the risk of dementia and Alzheimer's disease: a review of the literature

S Ouanes, J Popp - Frontiers in aging neuroscience, 2019 - frontiersin.org
Introduction: Cortisol effects on the brain are exerted through two distinct receptors, inducing
complex and even opposite effects on the cerebral structures implicated in the various …

[HTML][HTML] High anxiety trait: a vulnerable phenotype for stress-induced depression

M Weger, C Sandi - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
A great deal of research aims to identify risk factors related to individual vulnerability to
develop stress-induced psychopathologies. Here, we summarize evidence that point at …

Technostress and the hierarchical levels of personality: a two-wave study with multiple data samples

C Maier, S Laumer, J Wirth, T Weitzel - European Journal of …, 2019 - Taylor & Francis
Even though IS use has numerous benefits for users and organisations, such as improved
user performance and greater productivity, an increasing number of users experience …

Public health significance of neuroticism.

BB Lahey - American Psychologist, 2009 - psycnet.apa.org
The personality trait of neuroticism refers to relatively stable tendencies to respond with
negative emotions to threat, frustration, or loss. Individuals in the population vary markedly …

Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis

Y Chida, A Steptoe - Biological psychology, 2009 - Elsevier
The magnitude of the cortisol awakening response, a relatively new indicator of
hypothalamic–pituitary–adrenocortical (HPA) axis activation, has been related to a number …

Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study

SA Vreeburg, WJG Hoogendijk, J van Pelt… - Archives of general …, 2009 - jamanetwork.com
Context There is a central belief that depression is associated with hyperactivity of the
hypothalamic-pituitary-adrenal axis, resulting in higher cortisol levels. However, results are …

Cortisol and depression: three questions for psychiatry

J Herbert - Psychological medicine, 2013 - cambridge.org
BackgroundCortisol plays a multifaceted role in major depression disorder (MDD). Diurnal
rhythms are disturbed, there is increased resistance to the feedback action of …

Human models in acute and chronic stress: assessing determinants of individual hypothalamus–pituitary–adrenal axis activity and reactivity

BM Kudielka, S Wüst - Stress, 2010 - Taylor & Francis
Stress is one of the most significant health problems in modern societies and the 21st
century. This explains a pressing need for investigations into the biological pathways linking …

The cortisol awakening response and major depression: examining the evidence

K Dedovic, J Ngiam - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
A vast body of literature has revealed that dysregulation of the hypothalamic–pituitary–
adrenal (HPA) stress axis is associated with etiology of major depressive disorder (MDD) …

Is the cortisol awakening rise a response to awakening?

I Wilhelm, J Born, BM Kudielka, W Schlotz… - …, 2007 - Elsevier
A distinct rise in cortisol levels that occurs after morning awakening is increasingly used as
an indicator of adrenocortical activity which is associated with different pathologies …