Preconditioning the myocardium: from cellular physiology to clinical cardiology

DM Yellon, JM Downey - Physiological reviews, 2003 - journals.physiology.org
Yellon, Derek M., and James M. Downey. Preconditioning the Myocardium: From Cellular
Physiology to Clinical Cardiology. Physiol Rev 83: 1113-1151, 2003; 10.1152/physrev …

Myocardial stunning and hibernation revisited

G Heusch - Nature Reviews Cardiology, 2021 - nature.com
Unlike acute myocardial infarction with reperfusion, in which infarct size is the end point
reflecting irreversible injury, myocardial stunning and hibernation result from reversible …

Regional ischemic'preconditioning'protects remote virgin myocardium from subsequent sustained coronary occlusion.

K Przyklenk, B Bauer, M Ovize, RA Kloner, P Whittaker - circulation, 1993 - Am Heart Assoc
BACKGROUND One or more brief episodes of coronary artery occlusion protect or"
precondition" the myocardium perfused by that artery from a subsequent episode of …

Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop

RA Kloner, R Bolli, E Marban, L Reinlib, E Braunwald - Circulation, 1998 - Am Heart Assoc
On July 2–3, 1996, the National Heart, Lung, and Blood Institute sponsored a workshop in
Columbia, Md, entitled “The Medical and Cellular Implications of Myocardial Stunning …

Long-term benefit of postconditioning

H Thibault, C Piot, P Staat, L Bontemps, C Sportouch… - Circulation, 2008 - Am Heart Assoc
Background—We previously demonstrated that ischemic postconditioning decreases
creatine kinase release, a surrogate marker for infarct size, in patients with acute myocardial …

Ischaemic preconditioning: present position and future directions

DM Yellon, GF Baxter, D Garcia-Dorado… - Cardiovascular …, 1998 - academic.oup.com
Preconditioning the myocardium using short episodes of sublethal ischaemia will delay the
onset of necrosis during a subsequent lethal ischaemic insult. This powerful protective …

Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs

WG Toller, JR Kersten, PS Pagel… - The Journal of the …, 1999 - pubs.asahq.org
Background Recent evidence indicates that volatile anesthetics exert protective effects
during myocardial ischemia and reperfusion. The authors tested the hypothesis that …

Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits

H Takano, S Manchikalapudi, XL Tang, Y Qiu, A Rizvi… - Circulation, 1998 - Am Heart Assoc
Background—Despite intense investigation, the effector of the infarct-limiting protection
observed during the late phase of ischemic preconditioning (PC) remains unknown. The …

Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury

D Schulman, DS Latchman… - American Journal of …, 2001 - journals.physiology.org
Ischemic preconditioning (IP) reduces infarct size in young animals; however, its impact on
aging is underinvestigated. The effect of variations in IP stimuli was studied in young, middle …

Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs.

JZ Sun, XL Tang, SW Park, Y Qiu… - The Journal of …, 1996 - Am Soc Clin Investig
Conscious pigs underwent a sequence of 10 2-min coronary occlusions, each separated by
2 min of reperfusion, for three consecutive days (days 1, 2, and 3). On day 1, pigs received …