This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

The management of bronchial secretions is one of the main problems encountered in a wide
spectrum of medical conditions ranging from respiratory disorders, neuromuscular disorders …

A major role of respiratory mucus is to trap inhaled particles, including pathogens and
environmental particulates, to limit body exposure. Despite the tremendous health …

Conclusion This is the first extensive systematic literature review undertaken of the existing
evidence surrounding comprehensive physiotherapy management of the spontaneously …

Physiotherapy management is a key element of care for people with cystic fibrosis (CF)
throughout the lifespan. Although considerable evidence exists to support physiotherapy …

Background: Airway clearance may be impaired in disorders associated with abnormal
cough mechanics, altered mucus rheology, altered mucociliary clearance, or structural …

Background Chest physiotherapy is widely prescribed to assist the clearance of airway
secretions in people with cystic fibrosis. Oscillating devices generate intra‐or extra‐thoracic …

There has been extensive theoretical debate over whether population viscosity (limited
dispersal) can favour cooperation. While limited dispersal increases the probability of …

This review describes a framework for providing a personalised approach to selecting the
most appropriate airway clearance technique (ACT) for each patient. It is based on a …

Bronchial diseases are characterised by the weak efficiency of mucus transport through the
lower airways, leading in some cases to the muco-obstruction of bronchi. It has been …