Regulated cell death pathways in kidney disease
AB Sanz, MD Sanchez-Niño, AM Ramos… - Nature Reviews …, 2023 - nature.com
Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …
Novel, emerging and provisional renal entities: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
Abstract The Genitourinary Pathology Society (GUPS) undertook a critical review of the
recent advances in renal neoplasia, particularly focusing on the newly accumulated …
recent advances in renal neoplasia, particularly focusing on the newly accumulated …
[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
Co-existence of ESC-RCC, EVT, and LOT as synchronous and metachronous tumors in six patients with multifocal neoplasia but without clinical features of tuberous …
LA Lerma, GR Schade, MS Tretiakova - Human Pathology, 2021 - Elsevier
Renal cell tumors with oncocytic phenotypes represent a daily challenge, with several novel,
emerging, and provisional entities enriching the diagnostic repertoire. Eosinophilic solid and …
emerging, and provisional entities enriching the diagnostic repertoire. Eosinophilic solid and …
Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets
J Lu, Y Ding, Y Chen, J Jiang, Y Chen, Y Huang… - Nature …, 2021 - nature.com
Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of
gastric cancer. However, little is known about the genomic features of this disease. We …
gastric cancer. However, little is known about the genomic features of this disease. We …
[HTML][HTML] Do we need an updated classification of oncocytic renal tumors?: Emergence of low-grade oncocytic tumor (LOT) and eosinophilic vacuolated tumor (EVT) as …
O Hes, K Trpkov - Modern Pathology, 2022 - Elsevier
The category of “oncocytic renal tumors''includes well-recognized entities, such as renal
oncocytoma (RO) and eosinophilic variant of chromophobe renal cell carcinoma (eo …
oncocytoma (RO) and eosinophilic variant of chromophobe renal cell carcinoma (eo …
[HTML][HTML] From kidney injury to kidney cancer
Epidemiological studies document strong associations between acute or chronic kidney
injury and kidney tumors. However, whether these associations are linked by causation, and …
injury and kidney tumors. However, whether these associations are linked by causation, and …
Renal cell carcinoma associated with tuberous sclerosis complex (TSC)/mammalian target of rapamycin (MTOR) genetic alterations
P Argani, R Mehra - Modern Pathology, 2022 - nature.com
The majority of hereditary tumor syndromes involve germline mutations, which effectively
inactivate tumor suppressor genes (for example TSC1 and TSC2), whereby cells with a bi …
inactivate tumor suppressor genes (for example TSC1 and TSC2), whereby cells with a bi …
Xanthomatous Giant Cell Renal Cell Carcinoma: Another Morphologic Form of: TSC:-associated Renal Cell Carcinoma
Over the past decade, several distinct novel renal epithelial neoplasms driven by underlying
tuberous sclerosis comples (TSC)/mammalian target of rapamycin (MTOR) pathway …
tuberous sclerosis comples (TSC)/mammalian target of rapamycin (MTOR) pathway …
Acquired Cystic Disease-Associated Renal Cell Carcinoma: A Systematic Review and Meta-analysis
Acquired cystic disease-associated renal cell carcinoma (ACD-RCC) is a common subtype
of renal cell carcinoma (RCC) in end-stage renal disease (ESRD) patients. The current …
of renal cell carcinoma (RCC) in end-stage renal disease (ESRD) patients. The current …