Epigenetic programming and fetal metabolic programming

Z Zhu, F Cao, X Li - Frontiers in endocrinology, 2019 - frontiersin.org
Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

Epigenetics and the Developmental Origins of Health and Disease: Parental environment signalling to the epigenome, critical time windows and sculpting the adult …

S Safi-Stibler, A Gabory - Seminars in cell & developmental biology, 2020 - Elsevier
Abstract The literature about Developmental Origins of Health and Disease (DOHaD)
studies is considerably growing. Maternal and paternal environment, during all the …

Obesity-induced inflammation exacerbates clonal hematopoiesis

SK Pasupuleti, B Ramdas, SS Burns… - The Journal of …, 2023 - Am Soc Clin Investig
Characterized by the accumulation of somatic mutations in blood cell lineages, clonal
hematopoiesis of indeterminate potential (CHIP) is frequent in aging and involves the …

Maternal obesity, maternal overnutrition and fetal programming: effects of epigenetic mechanisms on the development of metabolic disorders

E Şanlı, S Kabaran - Current genomics, 2019 - ingentaconnect.com
Background: Maternal obesity and maternal overnutrition, can lead to epigenetic alterations
during pregnancy and these alterations can influence fetal and neonatal phenotype which …

Maternal factors that induce epigenetic changes contribute to neurological disorders in offspring

A Banik, D Kandilya, S Ramya, W Stünkel, YS Chong… - Genes, 2017 - mdpi.com
It is well established that the regulation of epigenetic factors, including chromatic
reorganization, histone modifications, DNA methylation, and miRNA regulation, is critical for …

Prevalence of diabetes and obesity in association with prematurity and growth restriction

G Kopec, PS Shekhawat… - … , metabolic syndrome and …, 2017 - Taylor & Francis
Intrauterine growth restriction (IUGR) is when fetuses and newborn infants have not reached
their true growth potential as genetically defined. Fetuses with IUGR develop in a less than …

Maternal epigenetics and fetal and neonatal growth

S Kitsiou-Tzeli, M Tzetis - Current Opinion in Endocrinology …, 2017 - journals.lww.com
Maternal epigenetics and fetal and neonatal growth : Current Opinion in Endocrinology,
Diabetes and Obesity Maternal epigenetics and fetal and neonatal growth : Current Opinion in …

Biogenic phytochemicals modulating obesity: From molecular mechanism to preventive and therapeutic approaches

V Kumar, DD Singh, SS Lakhawat… - Evidence‐Based …, 2022 - Wiley Online Library
The incidence of obesity and over bodyweight is emerging as a major health concern.
Obesity is a complex metabolic disease with multiple pathophysiological clinical conditions …

Review shows that maternal obesity induces serious adverse neonatal effects and is associated with childhood obesity in their offspring

D Mitanchez, P Chavatte‐Palmer - Acta paediatrica, 2018 - Wiley Online Library
Aim Obesity at the start of pregnancy has been rising worldwide, increasing the risk of
maternal complications. We reviewed the independent effects of maternal obesity during …

Maternal obesity and prenatal programming

S Elshenawy, R Simmons - Molecular and cellular endocrinology, 2016 - Elsevier
Obesity is a significant and increasing public health concern in the United States and
worldwide. Clinical and epidemiological evidence clearly shows that genetic and …