Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding
J Sunter, K Gull - Open biology, 2017 - royalsocietypublishing.org
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The
evolutionary pressure associated with establishing and maintaining an infection and …
evolutionary pressure associated with establishing and maintaining an infection and …
Ciliary ectosomes: transmissions from the cell's antenna
CR Wood, JL Rosenbaum - Trends in cell biology, 2015 - cell.com
The cilium is the site of function for a variety of membrane receptors, enzymes and signal
transduction modules crucial for a spectrum of cellular processes. Through targeted …
transduction modules crucial for a spectrum of cellular processes. Through targeted …
Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection
Y Li, S Shah-Simpson, K Okrah, AT Belew… - PLoS …, 2016 - journals.plos.org
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite,
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology
RJ Wheeler, E Gluenz, K Gull - Molecular microbiology, 2011 - Wiley Online Library
The cell cycle is central to understanding fundamental biology of Leishmania, a group of
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …
Host–pathogen interaction in leishmaniasis: immune response and vaccination strategies
Leishmaniasis is a zoonotic and vector-borne infectious disease that is caused by the genus
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Leishmania belonging to the trypanosomatid family. The protozoan parasite has a digenetic …
Recent advances in chemotherapeutics for leishmaniasis: Importance of the cellular biochemistry of the parasite and its molecular interaction with the host
Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …
Leishmania tarentolae: Taxonomic classification and its application as a promising biotechnological expression host
In this review, we summarize the current knowledge concerning the eukaryotic protozoan
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …
parasite Leishmania tarentolae, with a main focus on its potential for biotechnological …
Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process
CL Forestier, C Machu, C Loussert, P Pescher… - Cell host & …, 2011 - cell.com
Leishmania donovani causes human visceral leishmaniasis. The parasite infectious cycle
comprises extracellular flagellated promastigotes that proliferate inside the insect vector …
comprises extracellular flagellated promastigotes that proliferate inside the insect vector …
Peptides to tackle leishmaniasis: Current status and future directions
AA Robles-Loaiza, EA Pinos-Tamayo… - International journal of …, 2021 - mdpi.com
Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …
the pharmaceutical industry. These molecules are currently being used in the development …
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
M Reverte, RO Eren, B Jha, C Desponds… - PLoS …, 2021 - journals.plos.org
The oxidative burst generated by the host immune system can restrict intracellular parasite
entry and growth. While this burst leads to the induction of antioxidative enzymes, the …
entry and growth. While this burst leads to the induction of antioxidative enzymes, the …