Remote ischemic conditioning: from bench to bedside

SY Lim, DJ Hausenloy - Frontiers in physiology, 2012 - frontiersin.org
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue
against the detrimental effects of acute ischemia-reperfusion injury (IRI). It describes an …

[HTML][HTML] Circulating mediators of remote ischemic preconditioning: search for the missing link between non-lethal ischemia and cardioprotection

M Billah, A Ridiandries, U Allahwala, H Mudaliar… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Acute myocardial infarction (AMI) is one of the leading causes of mortality and morbidity
worldwide. There has been an extensive search for cardioprotective therapies to reduce …

Limb ischemic preconditioning protects against contrast-induced nephropathy via renalase

F Wang, J Yin, Z Lu, G Zhang, J Li, T Xing, S Zhuang… - …, 2016 - thelancet.com
Clinical trials shows that remote ischemic preconditioning (IPC) can protect against contrast
induced nephropathy (CIN) in risky patients, however, the exact mechanism is unclear. In …

Apolipoprotein aI is a potential mediator of remote ischemic preconditioning

P Hibert, D Prunier-Mirebeau, O Beseme… - PloS one, 2013 - journals.plos.org
Background Remote ischemic preconditioning (RIPC) has emerged as an attractive strategy
in clinical settings. Despite convincing evidence of the critical role played by circulating …

RIPC for multiorgan salvage in clinical settings: evolution of concept, evidences and mechanisms

PK Randhawa, A Bali, AS Jaggi - European journal of pharmacology, 2015 - Elsevier
Ischemic preconditioning is an intrinsic process in which preconditioning ischemia (ischemia
of shorter duration) protects the organs against the subsequent index ischemia (sustained …

[HTML][HTML] Remote ischemic preconditioning in aortic valve surgery: results of a randomized controlled study

F Pinaud, JJ Corbeau, C Baufreton, JP Binuani… - Journal of …, 2016 - Elsevier
Background Although remote ischemic preconditioning (RIPC) has emerged as an attractive
strategy to reduce cardiac injury in patients undergoing diverse cardiac surgical procedures …

Metabolic signature of remote ischemic preconditioning involving a cocktail of amino acids and biogenic amines

JM Chao de la Barca, O Bakhta… - Journal of the …, 2016 - Am Heart Assoc
Background Remote ischemic preconditioning (RIPC) is an attractive therapeutic procedure
for protecting the heart against ischemia/reperfusion injury. Despite evidence of humoral …

The mitochondria-targeted antioxidants and remote kidney preconditioning ameliorate brain damage through kidney-to-brain cross-talk

DN Silachev, NK Isaev, IB Pevzner, LD Zorova… - PLoS …, 2012 - journals.plos.org
Background Many ischemia-induced neurological pathologies including stroke are
associated with high oxidative stress. Mitochondria-targeted antioxidants could rescue the …

The mitochondrion as a key regulator of ischaemic tolerance and injury

DN Silachev, EY Plotnikov, IB Pevzner… - Heart, Lung and …, 2014 - Elsevier
Vascular pathologies pose a significant health problem because of their wide prevalence
and high impact on the rate of mortality. Blockade of blood flow in major blood vessels leads …

Aged kidney: can we protect it? Autophagy, mitochondria and mechanisms of ischemic preconditioning

SS Jankauskas, DN Silachev, NV Andrianova… - Cell Cycle, 2018 - Taylor & Francis
The anti-aging strategy is one of the main challenges of the modern biomedical science. The
term “aging” covers organisms, cells, cellular organelles and their constituents. In general …