Synthetic strategies for thiazolopyridine derivatives

MS Nazir, A Nawaz, S Aslam, M Ahmad… - Synthetic …, 2023 - Taylor & Francis
Both thiazole and pyridine are well recognized heterocycles. The fusion of these two
heterocycles results in thiazolopyridine ring system, which is the part of a large number of …

[HTML][HTML] New 4-thiazolidinone-based molecules Les-2769 and Les-3266 as possible PPARγ modulators

M Bar, B Skóra, A Tabęcka-Łonczyńska, S Holota… - Bioorganic …, 2022 - Elsevier
Abstract Development of cancer drug-resistance is still an ongoing problem in the modern
anticancer treatment. Therefore, there is a need to search for a new active substance, which …

Spectro-electrochemical, fluorometric and biothermodynamic evaluation of pharmacologically active morpholine scaffold single crystal ligand and its metal (II) …

K Sakthikumar, RWM Krause, BK Isamura… - Journal of Inorganic …, 2022 - Elsevier
A novel series of metal (II) complexes (1–5)[M II (L) 2]{Where M= Cu (1), Co (2), Mn (3), Ni
(4) and Zn (5)} constructed from 2-(4-morpholinobenzylideneamino) phenol Schiff base …

Silver (I) complexes of the pharmaceutical agents metronidazole and 4-hydroxymethylpyridine: comparison of cytotoxic profile for potential clinical application

L Radko, S Stypuła-Trębas, A Posyniak, D Żyro… - Molecules, 2019 - mdpi.com
In previous papers, we have reported on the high antifungal and significant antibacterial
activity against Gram-positive and Gram-negative bacteria of the water-soluble silver (I) …

Density functional theory molecular modelling, DNA interactions, antioxidant, antimicrobial, anticancer and biothermodynamic studies of bioactive water soluble mixed …

K Sakthikumar, J Dhaveethu Raja… - Journal of …, 2019 - Taylor & Francis
A novel series of bioactive water soluble mixed ligand complexes (1–5)[MII (L)(phen) AcO]. n
H2O {where M= Cu (1) n= 2; Co (2), Mn (3), Ni (4), n= 4 and Zn (5) n= 2} were synthesized …

Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn (ii), Co (ii) and Ni (ii) complexes …

K Sakthikumar, BK Isamura, RWM Krause - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
A novel class of bioactive complexes (1–3)[MII (L) 2 (bpy)], where, L= 2-(4-
morpholinobenzylideneamino) phenol, bpy= 2, 2′-bipyridine, MII= Mn (1), Co (2) or Ni (3) …

Synthesis, spectroscopy, light stability, single-crystal analysis, and in vitro cytotoxic activity on HepG2 liver cancer of two novel silver (I) complexes of miconazole

K Stryjska, L Radko, L Chęcińska, J Kusz… - International Journal of …, 2020 - mdpi.com
Two novel silver (I) complexes of the biologically active ligand miconazole in the form of Ag
(MCZ) 2X (MCZ= 1-[2-(2, 4-dichlorobenzyloxy)-2-(2, 4-dichlorophenyl) ethyl]-1 H-imidazole]; …

[PDF][PDF] Synthesis of some С5 substituted 4-phenylimino-thiazolidin-2-ones as possible anti-inflammatory agents

CT Сhulovska Z, I Drapak… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Based on the Knoevenagel condensation, nitrosation, and azo coupling reactions, the
synthesis of some С5 substituted 4-phenylimino-thiazolidin-2-ones was carried out. The …

Multifunctional Silver (I) complexes with metronidazole drug reveal antimicrobial properties and antitumor activity against human hepatoma and colorectal …

D Żyro, L Radko, A Śliwińska, L Chęcińska, J Kusz… - Cancers, 2022 - mdpi.com
Simple Summary Our previous studies demonstrated that a silver (I) nitrate complex with
metronidazole presented greater photo-stability, antimicrobial, cytotoxic and genotoxic …

Recent advances in the synthesis of thiazolo [4, 5-b] pyridines. Part 2: Focus on thiazole annulation to pyridine ring (microreview)

TI Chaban, OV Klenina, IH Chaban… - Chemistry of Heterocyclic …, 2024 - Springer
Accepted after revision March 27, 2024 in different positions, as well as their ability to
interact with a wider range of receptor targets may become the factors of crucial importance …