Behavioral neuroscience of psychological pain
Pain is a common word used to refer to a wide range of physical and mental states sharing
hedonic aversive value. Three types of pain are distinguished in this article: Physical pain …
hedonic aversive value. Three types of pain are distinguished in this article: Physical pain …
Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia-and addiction-relevant features: The RHA vs. RLA rats
A Fernández-Teruel, I Oliveras, T Cañete… - Neuroscience & …, 2021 - Elsevier
Abstract The Roman High-(RHA) and Low-(RLA) avoidance rat lines/strains were generated
through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way …
through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way …
A genetic model of impulsivity, vulnerability to drug abuse and schizophrenia-relevant symptoms with translational potential: the roman high-vs. low-avoidance rats
O Giorgi, MG Corda… - Frontiers in behavioral …, 2019 - frontiersin.org
The bidirectional selective breeding of Roman high-(RHA) and low-avoidance (RLA) rats for
respectively rapid vs. poor acquisition of active avoidant behavior has generated two …
respectively rapid vs. poor acquisition of active avoidant behavior has generated two …
Reward loss and addiction: Opportunities for cross-pollination
Paradigms used to study the response to and consequences of exposure to reward loss
have been underutilized in approaches to the psychobiology of substance use disorders …
have been underutilized in approaches to the psychobiology of substance use disorders …
Anti-anxiety self-medication in rats: oral consumption of chlordiazepoxide and ethanol after reward devaluation
Rats increased preference for ethanol after sessions of appetitive extinction, but not after
acquisition (reinforced) sessions (Manzo et al., 2014). Drinking was not influenced by …
acquisition (reinforced) sessions (Manzo et al., 2014). Drinking was not influenced by …
[HTML][HTML] Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional …
Modulation of metabotropic glutamate 2 (mGlu2) receptor function has huge potential for
treating psychiatric and neurological diseases. Development of drugs acting on mGlu2 …
treating psychiatric and neurological diseases. Development of drugs acting on mGlu2 …
Relationship between ethanol preference and sensation/novelty seeking
L Manzo, MJ Gómez, JE Callejas-Aguilera… - Physiology & …, 2014 - Elsevier
High-and low-avoidance Roman inbred rat strains (RHA-I, RLA-I) were selected for extreme
differences in two-way active avoidance. RHA-I rats also express less anxiety than RLA-I …
differences in two-way active avoidance. RHA-I rats also express less anxiety than RLA-I …
Anti-anxiety self-medication induced by incentive loss in rats
L Manzo, MJ Gómez, JE Callejas-Aguilera… - Physiology & …, 2014 - Elsevier
Ethanol can be used to ameliorate negative emotion in anxiety-inducing situations. Two
experiments tested whether rats would increase preference for ethanol immediately after …
experiments tested whether rats would increase preference for ethanol immediately after …
Frustrative nonreward and emotional self-medication: Factors modulating alcohol consumption following reward downshift in rats
Life experience involving unexpected incentive loss (eg, loss of job or a significant other)
may result in negative emotional reactions (frustration) and promote alcohol drinking …
may result in negative emotional reactions (frustration) and promote alcohol drinking …
Short-term selection for high and low ethanol intake yields differential sensitivity to ethanol's motivational effects and anxiety-like responses in adolescent Wistar rats
MS Fernández, B Báez, A Bordón, L Espinosa… - Progress in Neuro …, 2017 - Elsevier
Alcohol use disorders are modulated by genetic factors, but the identification of specific
genes and their concomitant biological changes that are associated with a higher risk for …
genes and their concomitant biological changes that are associated with a higher risk for …