Lyme borreliosis

AC Steere, F Strle, GP Wormser, LT Hu… - Nature reviews Disease …, 2016 - nature.com
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of
the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in …

Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Current status of microbes involved in the degradation of pharmaceutical and personal care products (PPCPs) pollutants in the aquatic ecosystem

M Narayanan, M El-Sheekh, Y Ma, A Pugazhendhi… - Environmental …, 2022 - Elsevier
Contamination of aquatic systems with pharmaceuticals, personal care products, steroid
hormones, and agrochemicals has been an immense problem for the earth's ecosystem and …

Lyme disease pathogenesis

J Coburn, B Garcia, LT Hu, MW Jewett… - Current issues in …, 2021 - mdpi.com
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Lyme borreliosis–from tick bite to diagnosis and treatment

G Stanek, F Strle - FEMS microbiology reviews, 2018 - academic.oup.com
Lyme borreliosis is caused by certain genospecies of the Borrelia burgdorferi sensu lato
complex, which are transmitted by hard ticks of the genus Ixodes. The most common clinical …

Host association of Borrelia burgdorferi sensu lato: A review

KA Wolcott, G Margos, V Fingerle, NS Becker - Ticks and tick-borne …, 2021 - Elsevier
Borrelia burgdorferi sensu lato (Bbsl) is a bacterial species complex that includes the
etiological agents of the most frequently reported vector-borne disease in the Northern …

Hijacking factor H for complement immune evasion

SR Moore, SS Menon, C Cortes… - Frontiers in …, 2021 - frontiersin.org
The complement system is an essential player in innate and adaptive immunity. It consists of
three pathways (alternative, classical, and lectin) that initiate either spontaneously …

[HTML][HTML] Regulation of regulators: Role of the complement factor H-related proteins

M Cserhalmi, A Papp, B Brandus, B Uzonyi… - Seminars in …, 2019 - Elsevier
The complement system, while being an essential and very efficient effector component of
innate immunity, may cause damage to the host and result in various inflammatory …

Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex

BL Garcia, H Zhi, B Wager, M Höök, JT Skare - PLoS pathogens, 2016 - journals.plos.org
Pathogens that traffic in blood, lymphatics, or interstitial fluids must adopt strategies to evade
innate immune defenses, notably the complement system. Through recruitment of host …

Stage‐specific global alterations in the transcriptomes of L yme disease spirochetes during tick feeding and following mammalian host adaptation

R Iyer, MJ Caimano, A Luthra, D Axline Jr… - Molecular …, 2015 - Wiley Online Library
B orrelia burgdorferi, the agent of L yme disease, is maintained in nature within an enzootic
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …