The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …

Mitochondrial function declines with age, leading to a variety of age-related diseases
(metabolic, central nervous system-related, cancer, etc.) and medication usage increases …

Adiponectin (adipoq), the most abundant hormone in circulation, has many beneficial effects
on the cardiovascular system, in part by preserving the contractile phenotype of vascular …

The progress in understanding the pathogenesis and treatment of Alzheimer's disease (AD)
is based on the recognition of the primary causes of the disease, which can be deduced …

Sepsis is a life-threatening disease characterized by a defensive response to damage. The
immune response in patients with sepsis is overenhanced in the early stages and …

Assessment of drug-induced mitochondrial dysfunctions is important in drug development as
well as in the understanding of molecular mechanism of therapeutic or adverse effects of …

Vascular smooth muscle cell (VSMC) proliferation is a primary pathological event in the
development of atherosclerosis (AS), and the presence of homocysteine (Hcy) acts as an …

Glucose metabolic reprogramming from oxidative phosphorylation to glycolysis is one of the
hallmarks of cancer development. Coenzyme Q10 (CoQ10) is essential for electron transport …

Exact pathophysiological mechanisms of bipolar disorder have not been sufficiently clarified.
We review the evidence of mitochondrial dysfunctions on the relation between both disease …