Optical coherence tomography as a means to characterize visual pathway involvement in multiple sclerosis

CA Wicki, JVM Hanson… - Current opinion in …, 2018 - journals.lww.com
OCT provides insights into multiple sclerosis beyond the visual pathway. It is capable of
quantifying the major pathological hallmarks of the disease, specifically inflammation and …

Outcomes of natalizumab treatment within 3 years of relapsing-remitting multiple sclerosis diagnosis: a prespecified 2-year interim analysis of STRIVE

J Perumal, RJ Fox, R Balabanov, LJ Balcer, S Galetta… - BMC neurology, 2019 - Springer
Background STRIVE is a multicenter, observational, open-label, single-arm study of
natalizumab in anti–JC virus (JCV) seronegative patients with early relapsing-remitting …

Retinal optical coherence tomography measures in multiple sclerosis: a systematic review and meta‐analysis

NK El Ayoubi, A Ismail, F Fahd… - Annals of Clinical …, 2024 - Wiley Online Library
Spectral domain‐optical coherence tomography plays a crucial role in the early detection
and monitoring of multiple sclerosis (MS) pathophysiology. We aimed to quantify differences …

Retinal and choriocapillary vascular changes in early stages of multiple sclerosis: a prospective study

D Montorio, R Lanzillo, A Carotenuto… - Journal of Clinical …, 2021 - mdpi.com
Optical Coherence Tomography Angiography (OCTA) abnormalities occur in multiple
sclerosis (MS) over the course of the disease. OCTA investigations at early MS stages are …

Inner retinal layer changes reflect changes in ambulation score in patients with primary progressive multiple sclerosis

JA Gernert, L Böhm, M Starck, S Buchka… - International Journal of …, 2023 - mdpi.com
The establishment of surrogate markers to detect disability progression in persons with
multiple sclerosis (PwMS) is important to improve monitoring of clinical deterioration. Optical …

Progressive loss of corneal and retinal nerve fibers in patients with multiple sclerosis: a 2-year follow-up study

G Bitirgen, Z Akpinar, AU Uca… - … Vision Science & …, 2020 - tvst.arvojournals.org
Purpose: To determine longitudinal alterations in corneal nerve fiber morphology, dendritic
cell (DC) density, and retinal nerve fiber layer (RNFL) thickness over 2 years in patients with …

Retinal nerve fiber layer thickness in multiple sclerosis with and without optic neuritis: a four-year follow-up study from Oman

AS Al-Mujaini, MS Al-Mujaini, BI Sabt - BMC ophthalmology, 2021 - Springer
Background Multiple sclerosis (MS) is an autoimmune disease that attacks the central
nervous system, with optic neuritis (ON) being a common early manifestation. Retinal nerve …

[HTML][HTML] Abnormal dynamic pupillometry relates to neurologic disability and retinal axonal loss in patients with multiple sclerosis

G Bitirgen, Z Akpinar, HB Turk… - … Vision Science & …, 2021 - iovs.arvojournals.org
Purpose: To assess alterations in quantitative dynamic pupil responses to light in relation to
neurologic disability and retinal axonal loss in patients with multiple sclerosis (MS) …

Long-term effect of permanent demyelination on axonal survival in multiple sclerosis

A Klistorner, S Klistorner, Y You… - Neurology …, 2022 - AAN Enterprises
Background and Objectives To investigate the long-term effect of permanent demyelination
on axonal attrition by examining an association between intereye asymmetry of the …

Clinical effects associated with five-year retinal nerve fiber layer thinning in multiple sclerosis

D Jakimovski, R Zivadinov, CB Vaughn, O Ozel… - Journal of the …, 2021 - Elsevier
Background Neurodegenerative changes in multiple sclerosis (MS) are associated with long-
term disability progression (DP). Optical coherence tomography (OCT) measures may be …