Genetics of bipolar disorder

B Kerner - The application of clinical genetics, 2014 - Taylor & Francis
Bipolar disorder is a common, complex genetic disorder, but the mode of transmission
remains to be discovered. Many researchers assume that common genomic variants carry …

Chondroitin sulfate proteoglycans: Structure‐function relationship with implication in neural development and brain disorders

S Avram, S Shaposhnikov, C Buiu… - BioMed research …, 2014 - Wiley Online Library
Chondroitin sulfate proteoglycans (CSPGs) are extracellular matrix components that contain
two structural parts with distinct functions: a protein core and glycosaminoglycan (GAG) side …

Decreased density of perineuronal net in prelimbic cortex is linked to depressive-like behavior in young-aged rats

Z Yu, N Chen, D Hu, W Chen, Y Yuan… - Frontiers in molecular …, 2020 - frontiersin.org
Perineuronal nets (PNNs) are condensed extracellular matrix (ECM) structures regulating
developmental plasticity and protecting neurons against oxidative stress. PNN abnormalities …

Fine structure analysis of perineuronal nets in the ketamine model of schizophrenia

R Kaushik, N Lipachev, G Matuszko… - European Journal of …, 2021 - Wiley Online Library
Perineuronal nets (PNNs) represent a highly condensed specialized form of brain
extracellular matrix (ECM) enwrapping mostly parvalbumin‐positive interneurons in the …

ADAMTS-12: functions and challenges for a complex metalloprotease

Y Mohamedi, T Fontanil, S Cal, T Cobo… - Frontiers in Molecular …, 2021 - frontiersin.org
Nineteen members of the ADAMTS family of secreted zinc metalloproteinases are present in
the human degradome. A wide range of different functions are being attributed to these …

New insights into ADAMTS metalloproteases in the central nervous system

Y Mohamedi, T Fontanil, T Cobo, S Cal, AJ Obaya - Biomolecules, 2020 - mdpi.com
Components of the extracellular matrix (ECM) are key players in regulating cellular functions
throughout the whole organism. In fact, ECM components not only participate in tissue …

[HTML][HTML] Extracellular matrixes and neuroinflammation

DG Jang, HJ Sim, EK Song, T Kwon, TJ Park - BMB reports, 2020 - ncbi.nlm.nih.gov
The extracellular matrix is a critical component of every human tissue. ECM not only
functions as a structural component but also regulates a variety of cellular processes such …

Chondroitin sulfate proteoglycans mRNA expression and degradation in the zebra finch following traumatic brain injury

A Talwalkar, G Haden, KA Duncan - Journal of Chemical Neuroanatomy, 2024 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.
From minutes to months following damage, injury can result in a complex pathophysiology …