Computer‐assisted synthetic planning: the end of the beginning

S Szymkuć, EP Gajewska, T Klucznik… - Angewandte Chemie …, 2016 - Wiley Online Library
Exactly half a century has passed since the launch of the first documented research project
(1965 Dendral) on computer‐assisted organic synthesis. Many more programs were created …

Epicoccum species: ubiquitous plant pathogens and effective biological control agents

JD Taguiam, E Evallo, MA Balendres - European Journal of Plant …, 2021 - Springer
Epicoccum species are ubiquitous ascomycetes. Several species are known to cause plant
diseases and some species act as biological control agents against a range of plant …

A pressure test to make 10 molecules in 90 days: external evaluation of methods to engineer biology

A Casini, FY Chang, R Eluere, AM King… - Journal of the …, 2018 - ACS Publications
Centralized facilities for genetic engineering, or “biofoundries”, offer the potential to design
organisms to address emerging needs in medicine, agriculture, industry, and defense. The …

Isolation of anticancer and anti-trypanosome secondary metabolites from the endophytic fungus Aspergillus flocculus via bioactivity guided isolation and MS based …

AF Tawfike, M Romli, C Clements, G Abbott… - … of Chromatography B, 2019 - Elsevier
This study aims to identify bioactive anticancer and anti-trypanosome secondary metabolites
from the fermentation culture of Aspergillus flocculus endophyte assisted by modern …

The biotechnological potential of Epicoccum spp.: diversity of secondary metabolites

RM Braga, G Padilla, WL Araújo - Critical reviews in microbiology, 2018 - Taylor & Francis
Epicoccum is a genus of ubiquitous fungi typically found in air, in soil, and on decaying
vegetation. They also commonly display an endophytic lifestyle and are isolated from …

Production of the anticancer drug taxol by the endophytic fungus Epicoccum nigrum TXB502: enhanced production by gamma irradiation mutagenesis and …

ESR El-Sayed, AG Zaki, AS Ahmed… - Applied Microbiology and …, 2020 - Springer
Taxol, a phyto-extracted diterpenoid, is the most commercially needed drug in cancer
chemotherapy. In spite of the microbial production of taxol being successful and prospective …

[图书][B] Industrially important fungi for sustainable development

AM Abdel-Azeem, AN Yadav, N Yadav, Z Usmani - 2021 - Springer
Fungi are an essential, fascinating, and biotechnologically useful group of organisms with
an incredible biotechnological potential for industrial exploitation. Knowledge of the world's …

Melleins—Intriguing natural compounds

P Reveglia, M Masi, A Evidente - Biomolecules, 2020 - mdpi.com
Melleins are 3, 4-dihydroisocoumarins mainly produced by fungi, but also by plants, insects
and bacteria. These specialized metabolites play important roles in the life cycles of the …

Protein Kinase and HDAC Inhibitors from the Endophytic Fungus Epicoccum nigrum

M El Amrani, D Lai, A Debbab, AH Aly… - Journal of natural …, 2014 - ACS Publications
A chemical investigation of the endophytic fungus Epicoccum nigrum isolated from leaves of
Mentha suaveolens collected in Morocco resulted in the isolation of five new polyketides …

Aureochaeglobosins A–C, Three [4 + 2] Adducts of Chaetoglobosin and Aureonitol Derivatives from Chaetomium globosum

MH Yang, ML Gu, C Han, XJ Guo, GP Yin, P Yu… - Organic …, 2018 - ACS Publications
Aureochaeglobosins A–C (1–3), three novel [4+ 2] cycloaddition heterodimers of
chaetoglobosin and aureonitol derivatives, were obtained from the culture of endophytic …