Many thousands of lipid species exist and their metabolism is interwoven via numerous
pathways and networks. These networks can also change in response to cellular …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

The focus of the present study was to define the human plasma lipidome and to establish
novel analytical methodologies to quantify the large spectrum of plasma lipids. Partial lipid …

The spectrum of nonalcoholic fatty liver disease (NAFLD) includes steatosis, nonalcoholic
steatohepatitis (NASH), and cirrhosis. Recognition and timely diagnosis of these different …

Aflatoxins and fumonisins (FB) are mycotoxins contaminating a large fraction of the world's
food, including maize, cereals, groundnuts and tree nuts. The toxins frequently co-occur in …

Intensive research over the past 2 decades has implicated ceramide in the regulation of
several cell responses. However, emerging evidence points to dramatic complexities in …

Background Identifying mechanisms of diseases with complex inheritance patterns, such as
macular telangiectasia type 2, is challenging. A link between macular telangiectasia type 2 …

The primary goal of nursery pig management is making a smooth weaning transition to
minimize weaning associated depressed growth and diseases. Weaning causes …

Most research on human pancreatic islets is conducted on samples obtained from
normoglycaemic or diseased brain-dead donors and thus cannot accurately describe the …

Apoptosis and autophagy are two evolutionarily conserved processes that maintain
homeostasis during stress. Although the two pathways utilize fundamentally distinct …