The unique microenvironment of solid tumors, including desmoplasia within the extracellular
matrix, enhanced vascular permeability, and poor lymphatic drainage, leads to an elevated …

Objective The objective of this work was to study microbubble-enhanced temperature
elevation with high-intensity focused ultrasound (HIFU) at different acoustic pressures and …

Chemotherapy efficacy is often reduced by insufficient drug uptake in tumor cells. The
combination of ultrasound and microbubbles (USMB) has been shown to improve drug …

High-intensity focused ultrasound (HIFU) is a non-invasive tool that can be used for targeted
thermal ablation treatments. Currently, HIFU is clinically approved for treatment of uterine …

Objective The aim of this study is to describe a comprehensive contrast-enhanced
ultrasound (CEUS) imaging protocol and analysis method to implement CEUS LI-RADS …

Limited work has been reported on the acoustic and physical characterization of protein-
shelled UCAs. This study characterized bovine serum albumin (BSA)-shelled microbubbles …

To investigate the feasibility and tolerability of ultrasound and microbubbles (USMB)-
enhanced chemotherapy delivery for head and neck cancer, we performed a veterinary trial …

Sonazoid, an ultrasound contrast agent, has been covered by insurance in Japan since
January 2007 for the diagnosis of hepatic mass lesions and is widely used for diagnosing …

Bubble cluster dynamics in viscoelastic media is instructive for ultrasound diagnosis and
therapy. In this paper, we propose a statistical model for bubble cluster dynamics in …

Objective. Bacterial biofilms represent a major challenge for effective antibiotic therapy as
they confer physical and functional changes that protect bacteria from their surrounding …