Molecular mechanisms of ferroptosis and relevance to inflammation

L Deng, S He, N Guo, W Tian, W Zhang, L Luo - Inflammation Research, 2023 - Springer
Introduction Inflammation is a defensive response of the organism to irritation which is
manifested by redness, swelling, heat, pain and dysfunction. The inflammatory response …

Luteolin, a potent anticancer compound: from chemistry to cellular interactions and synergetic perspectives

H Singh Tuli, P Rath, A Chauhan, K Sak, D Aggarwal… - Cancers, 2022 - mdpi.com
Simple Summary Common flavonoid luteolin 3′, 4′, 5, 7-tetrahydroxyflavone has
immense potential to be utilized as a chemopreventive dietary molecule. According to …

The mechanisms of ferroptosis under hypoxia

X Gao, W Hu, D Qian, X Bai, H He, L Li… - Cellular and Molecular …, 2023 - Springer
Ferroptosis is a new form of programmed cell death, which is characterized by the iron-
dependent accumulation of lipid peroxidation and increase of ROS, resulting in oxidative …

[HTML][HTML] Targeting Nrf2 for ferroptosis-based therapy: Implications for overcoming ferroptosis evasion and therapy resistance in cancer

J Lee, JL Roh - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2023 - Elsevier
Ferroptosis is a newly discovered form of programmed cell death caused by redox-active
iron-mediated lipid peroxidation. Ferroptosis exhibits a unique morphological phenotype …

Heme oxygenase modulation drives ferroptosis in TNBC cells

V Consoli, V Sorrenti, V Pittalà, K Greish… - International journal of …, 2022 - mdpi.com
The term ferroptosis refers to a peculiar type of programmed cell death (PCD) mainly
characterized by extensive iron-dependent lipid peroxidation. Recently, ferroptosis has been …

Ferroptosis—a new dawn in the treatment of organ ischemia–reperfusion injury

L Zhou, S Han, J Guo, T Qiu, J Zhou, L Shen - Cells, 2022 - mdpi.com
Ischemia–reperfusion (I/R) is a common pathological phenomenon that occurs in numerous
organs and diseases. It generally results from secondary damage caused by the recovery of …

Susceptibility of cervical cancer to dihydroartemisinin-induced ferritinophagy-dependent ferroptosis

H Shi, L Xiong, G Yan, S Du, J Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
The clinical therapeutics of cervical cancer is limited due to the drug resistance and
metastasis of tumor. As a novel target for antitumor therapy, ferroptosis is deemed to be …

Ferroptosis and its role in skeletal muscle diseases

Y Wang, Z Zhang, W Jiao, Y Wang, X Wang… - Frontiers in molecular …, 2022 - frontiersin.org
Ferroptosis is characterized by the accumulation of iron and lipid peroxidation products,
which regulates physiological and pathological processes in numerous organs and tissues …

Luteolin, a flavone ingredient: Anticancer mechanisms, combined medication strategy, pharmacokinetics, clinical trials, and pharmaceutical researches

M Shi, Z Chen, H Gong, Z Peng, Q Sun… - Phytotherapy …, 2024 - Wiley Online Library
Current pharmaceutical research is energetically excavating the pharmacotherapeutic role
of herb‐derived ingredients in multiple malignancies' targeting. Luteolin is one of the major …

Photodynamic therapy combined with ferroptosis is a synergistic antitumor therapy strategy

Y Huang, X Li, Z Zhang, L Xiong, Y Wang, Y Wen - Cancers, 2023 - mdpi.com
Simple Summary In this work, we focused on the synergistic antitumor effects of
photodynamic therapy and ferroptosis. First, we briefly introduced the basic theory of …