Somatostatin-positive gamma-aminobutyric acid interneuron deficits in depression: cortical microcircuit and therapeutic perspectives
The functional integration of external and internal signals forms the basis of information
processing and is essential for higher cognitive functions. This occurs in finely tuned cortical …
processing and is essential for higher cognitive functions. This occurs in finely tuned cortical …
The neurocircuitry of fear, stress, and anxiety disorders
LM Shin, I Liberzon - Neuropsychopharmacology, 2010 - nature.com
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …
research has focused on determining the brain circuits that underlie them. Research on the …
Protein lactylation induced by neural excitation
Lactate has diverse roles in the brain at the molecular and behavioral levels under
physiological and pathophysiological conditions. This study investigates whether lysine …
physiological and pathophysiological conditions. This study investigates whether lysine …
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology
This work was supported by National Institute of Health (NIH) grants MH-541380, MH-
77083, MH-69056, MH-58922, MH-42088, MH071537, and DA-019624; the Doris Duke …
77083, MH-69056, MH-58922, MH-42088, MH071537, and DA-019624; the Doris Duke …
Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics
B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2016 - Taylor & Francis
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
Revise the revised? New dimensions of the neuroanatomical hypothesis of panic disorder
In 2000, Gorman et al. published a widely acknowledged revised version of their 1989
neuroanatomical hypothesis of panic disorder (PD). Herein, a 'fear network'was suggested …
neuroanatomical hypothesis of panic disorder (PD). Herein, a 'fear network'was suggested …
Insula and anterior cingulate GABA levels in posttraumatic stress disorder: preliminary findings using magnetic resonance spectroscopy
IM Rosso, MR Weiner, DJ Crowley… - Depression and …, 2014 - Wiley Online Library
Background Increased reactivity of the insular cortex and decreased activity of the dorsal
anterior cingulate cortex (ACC) are seen in functional imaging studies of posttraumatic …
anterior cingulate cortex (ACC) are seen in functional imaging studies of posttraumatic …
Neuroimaging in anxiety disorders
K Engel, B Bandelow, O Gruber… - Journal of neural …, 2009 - Springer
Neuroimaging studies have gained increasing importance in validating neurobiological
network hypotheses for anxiety disorders. Functional imaging procedures and radioligand …
network hypotheses for anxiety disorders. Functional imaging procedures and radioligand …
Decreased GABA levels in anterior cingulate cortex/medial prefrontal cortex in panic disorder
Changes of various brain metabolites including γ-aminobutyric acid (GABA), measured by
1H-magnetic resonance spectroscopy (MRS), have been reported in panic disorder (PD) …
1H-magnetic resonance spectroscopy (MRS), have been reported in panic disorder (PD) …
[HTML][HTML] Impaired cholesterol metabolism, neurons, and neuropsychiatric disorders
SY Cheon - Experimental Neurobiology, 2023 - ncbi.nlm.nih.gov
Cholesterol metabolism plays an essential role in cellular functions (including as a
component of the plasma membrane, as an energy source, and in hormone production) …
component of the plasma membrane, as an energy source, and in hormone production) …