Targeting multiple signaling pathways in cancer: The rutin therapeutic approach
Z Nouri, S Fakhri, K Nouri, CE Wallace, MH Farzaei… - Cancers, 2020 - mdpi.com
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
[HTML][HTML] A comprehensive review on secondary metabolites and health-promoting effects of edible lichen
Lichens have been concerned by many researchers because of their unique secondary
metabolites. However, the research on edible lichens is still lacking. This review collected …
metabolites. However, the research on edible lichens is still lacking. This review collected …
Anticancer potential of lichens' secondary metabolites
Lichens produce different classes of phenolic compounds, including anthraquinones,
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …
xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed …
Natural products as important tyrosine kinase inhibitors
B Yin, DM Fang, XL Zhou, F Gao - European journal of medicinal chemistry, 2019 - Elsevier
As an important source of drugs, natural products play an important role in the discovery and
development of new drugs. More than 60% of anti-tumor drugs are closely related to natural …
development of new drugs. More than 60% of anti-tumor drugs are closely related to natural …
Bispecific c-Met/PD-L1 CAR-T cells have enhanced therapeutic effects on hepatocellular carcinoma
W Jiang, T Li, J Guo, J Wang, L Jia, X Shi… - Frontiers in …, 2021 - frontiersin.org
T cells expressing chimeric antigen receptors, especially CD19 CAR-T cells have exhibited
effective antitumor activities in B cell malignancies, but due to several factors such as …
effective antitumor activities in B cell malignancies, but due to several factors such as …
Lichen depsidones with biological interest
Depsidones are some of the most abundant secondary metabolites produced by lichens.
These compounds have aroused great pharmacological interest due to their activities as …
These compounds have aroused great pharmacological interest due to their activities as …
Bioactive lichen secondary metabolites and their presence in species from Chile
E Poulsen-Silva, F Gordillo-Fuenzalida, C Atala… - Metabolites, 2023 - mdpi.com
Lichens are symbiotic organisms composed of at least one fungal and one algal species.
They are found in different environments around the world, even in the poles and deserts …
They are found in different environments around the world, even in the poles and deserts …
The Natural Products and Extracts: Anti‐Triple‐Negative Breast Cancer in Vitro
H Chen, J Yang, Y Yang, J Zhang, Y Xu… - Chemistry & …, 2021 - Wiley Online Library
Triple‐negative breast cancer (TNBC) makes up 15% to 20% of all breast cancer (BC)
cases, and represents one of the most challenging malignancies to treat. For many years …
cases, and represents one of the most challenging malignancies to treat. For many years …
Immunotherapy for hepatocellular carcinoma
M Zhou, B Liu, J Shen - Clinical and Experimental Medicine, 2023 - Springer
Hepatocellular carcinoma (HCC), a primary malignancy of the liver, is a threat to the health
of all humans as a prevalent malignancy and is the sixth most common cancer worldwide. It …
of all humans as a prevalent malignancy and is the sixth most common cancer worldwide. It …
Unraveling the pharmacological potential of lichen extracts in the context of cancer and inflammation with a broad screening approach
R Ingelfinger, M Henke, L Roser, T Ulshöfer… - Frontiers in …, 2020 - frontiersin.org
Lichen-forming fungi are symbiotic organisms that synthesize unique natural products with
potential for new drug leads. Here, we explored the pharmacological activity of six lichen …
potential for new drug leads. Here, we explored the pharmacological activity of six lichen …