Regeneration and tissue repair processes consist of a sequence of molecular and cellular
events which occur after the onset of a tissue lesion in order to restore the damaged tissue …

The problem of drug-induced hERG channel blockade, which can lead to acquired long QT
syndrome and potentially fatal arrhythmias, has exercised drug developers and regulatory …

Objective To study the biological effects of resveratrol on the growth, electrophysiology, and
mitochondrial function of human granulosa cells (h-GCs). Design Preclinical study. Setting …

In dogs and in humans, potassium channels formed by ether-a-go-go-related gene 1 protein
ERG1 (KCNH2) and KCNQ1 α-subunits, in association with KCNE β-subunits, play a role in …

Kv1 potassium channels are widely distributed in mammalian tissues and are involved in a
variety of functions from controlling the firing rate of neurons to maturation of T-lymphocytes …

KCNQ1 (Kv7. 1 or KvLQT1) encodes the alpha‐subunit of a voltage‐gated potassium
channel found in tissues including heart, brain, epithelia and smooth muscle. Tissue …

Progesterone production by the corpus luteum is a process vital for reproduction. In humans
its secretion is stimulated by the placental hormone human chorionic gonadotropin (hCG) …

Transmission distortion of disease-causing alleles in long QT syndrome (LQTS) has been
reported, suggesting a potential role of KCNQ1 and KCNH2 in reproduction. This study …

Whole cell perforated patch-clamp experiments were performed with adult rat alveolar
epithelial cells. The holding potential was− 60 mV, and depolarizing voltage steps activated …

This investigation determined the effects of K+ channel antagonists on proliferation,
differentiation, and apoptosis of porcine granulosa cells. The drugs screened for functional …