Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Small molecule as fluorescent probes for monitoring intracellular enzymatic transformations

H Singh, K Tiwari, R Tiwari, SK Pramanik… - Chemical …, 2019 - ACS Publications
All cellular processes are the results of synchronized actions of several intracellular
biochemical pathways. Recent emphasis is to visualize such pathways using appropriate …

All-in-One Alkaline Phosphatase-Response Aggregation-Induced Emission Probe for Cancer Discriminative Imaging and Combinational Chemodynamic …

LH Xiong, L Yang, J Geng, BZ Tang, X He - ACS nano, 2024 - ACS Publications
Currently, specific cancer-responsive fluorogenic probes with activatable imaging and
therapeutic functionalities are in great demand in the accurate diagnostics and efficient …

An activatable AIEgen probe for high‐fidelity monitoring of overexpressed tumor enzyme activity and its application to surgical tumor excision

H Li, Q Yao, F Xu, Y Li, D Kim, J Chung… - Angewandte …, 2020 - Wiley Online Library
Monitoring fluctuations in enzyme overexpression facilitates early tumor detection and
excision. An AIEgen probe (DQM‐ALP) for the imaging of alkaline phosphatase (ALP) …

A comprehensive overview on alkaline phosphatase targeting and reporting assays

SM Shaban, SB Jo, E Hafez, JH Cho, DH Kim - Coordination Chemistry …, 2022 - Elsevier
Alkaline phosphatase (ALP) is an enzyme that catalyzes the dephosphorylation of various
vital nucleic acids and proteins. A broad range of physiological and pathological processes …

Assays for alkaline phosphatase activity: Progress and prospects

Z Tang, H Chen, H He, C Ma - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Alkaline phosphatase (ALP) has become a representative enzyme of modern life industries.
As a critical biomarker of numerous diseases and a major tool enzyme of experiments …

Ratiometric two-photon fluorescence probes for sensing, imaging and biomedicine applications at living cell and small animal levels

H Jin, M Yang, Z Sun, R Gui - Coordination Chemistry Reviews, 2021 - Elsevier
The unique two-photon excitable luminescence and dual-emission ratio output features
endow organic molecule-based ratiometric two-photon fluorescence (RTPF) probes as …

Recent progress of fluorescent probes for the detection of alkaline phosphatase (ALP): A review

H Zhang, Q Ju, S Pang, N Wei, Y Zhang - Dyes and Pigments, 2021 - Elsevier
Alkaline phosphatase (ALP) that is a crucial biomarker for the diagnosis of hepatobiliary and
skeletal diseases is widely distributed in human bone, liver, intestine, placenta and other …

Fluorescent probes for the detection of alkaline phosphatase in biological systems: Recent advances and future prospects

K Wang, W Wang, XY Zhang, AQ Jiang… - TrAC Trends in …, 2021 - Elsevier
Alkaline phosphatase (ALP), an important enzyme in living organisms, plays significant roles
in the hydrolysis of phosphate groups from nucleic acids, proteins, and other substrates …

Single-molecule biosensing of alkaline phosphatase in cells and serum based on dephosphorylation-triggered catalytic assembly and disassembly of the fluorescent …

F Ma, N Zhao, M Liu, Q Xu, C Zhang - Analytical Chemistry, 2022 - ACS Publications
Alkaline phosphatase (ALP) is a valuable biomarker and effective therapeutic target for the
diagnosis and treatment of diverse human diseases, including bone disorder …