Introduction: Tigecycline, a derivative of minocycline, is an extended-spectrum antimicrobial
agent. It has a restricted approval field in children and the experience of its adoption in …

Purpose A patient with carbapenem-resistant Klebsiella pneumoniae infection is described,
and treatment options are discussed. Summary Few antibiotics to treat carbapenem …

Background: Nosocomial meningitis with multidrug-resistant (MDR) or extensively drug-
resistant (XDR) Acinetobacter baumannii is a life-threatening complication in neurosurgery …

We report the fourth case of Carbapenem-resistant Klebsiella pneumoniae (CRKP)
meningitis and the only one associated with brain abscess formation. A 29-years-old male …

Interventions: On the advice of a clinical pharmacist, the patient was given tigecycline (100
mg IV+ 3 mg IVT q12h) combined with amikacin (0.8 g IV+ 30 mg IVT qd) antiinfective …

Background Ventriculoperitoneal (VP) shunt infection, which is 1 of the most important
complications of VP shunt is observed at a rate of 4%–17%. Staphylococcus epidermidis is …

Ventriculoperitoneal (VP) shunt infections are seen in 3%–17% of patients with VP shunts.
These infections may cause severe morbidity and mortality. Staphylococci are the most …

Severe infection is a primary cause of mortality in children facing challenges from multidrug-
resistant (MDR) pathogens, particularly MDR Acinetobacter baumannii. Tigecycline has an …

Objective The aim of this study was to evaluate the efficacy and safety of salvage therapy of
tigecycline in critically ill children with infections caused by multidrug-resistant …

OBJECTIVE Cerebrospinal fluid (CSF) shunt infections caused by gram-negative bacteria
are difficult to treat given the limited treatment options and the emergence of carbapenem …