There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …

Relaxin, insulin-like peptide 3 (INSL3), relaxin-3, and INSL5 are the cognate ligands for the
relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates pleiotropic …

Neuropeptide S (NPS) is a recently discovered peptide shown to be involved in the
modulation of arousal and fear responses. It has also been shown that lateral ventricle …

Abstract Relaxin‐3 (RLN3) and its native receptor, relaxin family peptide 3 receptor
(RXFP3), constitute a newly identified neuropeptide system enriched in mammalian brain …

Relaxin‐3 is a member of a superfamily of structurally‐related peptides that includes relaxin
and insulin‐like peptide hormones. Soon after the discovery of the relaxin‐3 gene, relaxin‐3 …

Relaxin-3 is a member of the human relaxin peptide family, the gene for which, RLN3, is
predominantly expressed in the brain. Mapping studies in the rodent indicate a highly …

Both relaxin-3 and its receptor (GPCR135) are expressed predominantly in brain regions
known to play important roles in processing sensory signals. Recent studies have shown …

The relaxin-3 gene was identified in 2001 by searching the human genome database for
homologues of the relaxin hormone, and was subsequently discovered to encode a highly …

The relaxin family peptides, although structurally closely related to insulin, act on a group of
four G protein‐coupled receptors now known as Relaxin Family Peptide (RXFP) Receptors …

Relaxin-3 is a recently discovered neuropeptide and the results of earlier anatomical and
pharmacological studies suggest it plays a physiological role in modulating functions such …