[HTML][HTML] Resistance to thyroid hormone beta: a focused review

T Pappa, S Refetoff - Frontiers in endocrinology, 2021 - frontiersin.org
Resistance to thyroid hormone (RTH) is a clinical syndrome defined by impaired sensitivity
to thyroid hormone (TH) and its more common form is caused by mutations in the thyroid …

Endocrine tumours: thyrotropin-secreting pituitary adenoma: a structured review of 535 adult cases

C De Herdt, E Philipse… - European Journal of …, 2021 - academic.oup.com
Background and aims Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare
entity, occurring in one per million people. We performed a systematic review of 535 adult …

Thyrotropin-secreting pituitary adenomas: epidemiology, diagnosis, and management

FG Amlashi, NA Tritos - Endocrine, 2016 - Springer
Inappropriate secretion of TSH was first described in 1960 in a patient with evidence of
hyperthyroidism and expanded sella on imaging. It was later found that a type of pituitary …

Clinical features and therapeutic outcomes of GH/TSH cosecreting pituitary adenomas: experience of a single pituitary center

N Yu, L Duan, F Hu, S Yang, J Liu, M Chen… - Frontiers in …, 2023 - frontiersin.org
Background Growth hormone (GH)/thyroid stimulating hormone (TSH) cosecreting pituitary
adenoma (PA) is an exceedingly rare kind of bihormonal pituitary neuroendocrine tumors …

Thyrotropin-secreting pituitary adenomas

P Beck-Peccoz, L Persani, S Mantovani, D Cortelazzi… - Metabolism, 1996 - Elsevier
Normal or elevated thyrotropin (TSH) levels in hyperthyroid patients are characteristic of rare
TSH-secreting pituitary adenoma (TSH-oma), which is easily detectable by computed …

[HTML][HTML] Impaired sensitivity to thyroid hormone: defects of transport, metabolism, and action

AM Dumitrescu, M Korwutthikulrangsri… - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Resistance to thyroid hormone (RTH), a syndrome of reduced responsiveness of target
tissues to thyroid hormone (TH) was identified in 1967 (1). An early report proposed various …

[HTML][HTML] Synergistic signaling of KRAS and thyroid hormone receptor β mutants promotes undifferentiated thyroid cancer through MYC up-regulation

X Zhu, L Zhao, JW Park, MC Willingham, S Cheng - Neoplasia, 2014 - Elsevier
Undifferentiated thyroid carcinoma is one of the most aggressive human cancers with
frequent RAS mutations. How mutations of the RAS gene contribute to undifferentiated …

Thyrotropin in the development and management of differentiated thyroid cancer

DSA McLeod - Endocrinology and Metabolism Clinics, 2014 - endo.theclinics.com
Over the past decade, knowledge of the potential role of TSH in the development of
differentiated thyroid cancer has expanded. In addition, the therapeutic role of TSH has …

A challenging TSH/GH co-secreting pituitary adenoma with concomitant thyroid cancer; a case report and literature review

JH Yoon, W Choi, JY Park, AR Hong, SS Kim… - BMC Endocrine …, 2021 - Springer
Background Thyroid stimulating hormone (TSH) secreting pituitary adenoma (TSHoma) with
coexisting thyroid cancer is extremely rare, and proper treatment of both diseases may pose …

Is the incidence of differentiated thyroid cancer increased in patients with thyrotropin-secreting adenomas? Report of three cases from a large consecutive series

F Perticone, F Pigliaru, S Mariotti, L Deiana, L Furlani… - Thyroid, 2015 - liebertpub.com
Background: Patients with a thyrotropin-secreting pituitary adenoma (TSHoma) are exposed
to unregulated and inappropriately high levels of thyrotropin (TSH). Given the rarity of this …