Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
Thiazole: A versatile standalone moiety contributing to the development of various drugs and biologically active agents
For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …
Pyridine compounds with antimicrobial and antiviral activities
M Marinescu, CV Popa - International journal of molecular sciences, 2022 - mdpi.com
In the context of the new life-threatening COVID-19 pandemic caused by the SARS-CoV-2
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
virus, finding new antiviral and antimicrobial compounds is a priority in current research …
Recent advances in pyridine scaffold: Focus on chemistry, synthesis, and antibacterial activities
Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …
[HTML][HTML] Novel arylazo nicotinate derivatives as effective antibacterial agents: Green synthesis, molecular modeling, and structure-activity relationship studies
MR Eletmany, MA Albalawi, RAK Alharbi… - Journal of Saudi …, 2023 - Elsevier
A series of novel arylazo nicotinates compounds, denoted as (3a-k and 5a-d) were
synthesized and characterized through the reaction of 3-oxo-arylhydrazonals with various …
synthesized and characterized through the reaction of 3-oxo-arylhydrazonals with various …
Synthesis, anti-proliferative activity, gene expression, docking and DFT investigation of novel pyrazol-1-yl-thiazol-4 (5H)-one derivatives
In this elucidation, the novel thaizolone derivatives 8a-n were synthesised via the reaction
between thioamide derivatives 4a, b with chloroacetic acid and the appropriate aldehyde …
between thioamide derivatives 4a, b with chloroacetic acid and the appropriate aldehyde …
Molecular guidelines for promising antimicrobial agents
M Rzycki, M Gładysiewicz-Kudrawiec, S Kraszewski - Scientific Reports, 2024 - nature.com
Antimicrobial resistance presents a pressing challenge to public health, which requires the
search for novel antimicrobial agents. Various experimental and theoretical methods are …
search for novel antimicrobial agents. Various experimental and theoretical methods are …
[HTML][HTML] Advance in green synthesis of pharmacological important heterocycles using multicomponent reactions and magnetic nanocatalysts (MNCs)
D Zeleke, T Damena - Results in Chemistry, 2024 - Elsevier
The ever-increasing environmental pollution and its health concerns appeal replacement of
conventional organic synthesis with green synthetic methodology. This review presented …
conventional organic synthesis with green synthetic methodology. This review presented …
[HTML][HTML] Thiazole ring-the antimicrobial, anti-inflammatory, and anticancer active scaffold
S Hosseininezhad, A Ramazani - Arabian Journal of Chemistry, 2023 - Elsevier
Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …
Unravelling the thermodynamics and binding interactions of bovine serum albumin (BSA) with thiazole based carbohydrazide: Multi-spectroscopic, DFT and molecular …
In the present manuscript, a novel 2-((4-chlorophenyl) amino)-N'-(4-(diethylamino)-2-
hydroxybenzylidene) thiazole-4-carbohydrazide (H1) has been synthesized and …
hydroxybenzylidene) thiazole-4-carbohydrazide (H1) has been synthesized and …