The toxicity of antineoplastic drugs has been well known since they were introduced in the
1940s. Because most antineoplastic drugs are nonselective in their mechanism of action …

In order to assess occupational exposure of hospital personnel involved in the preparation
and administration of antineoplastic drugs, biological and environmental monitoring are …

Профессиональные заболевания медицинских работников многообразны и по
нозологии. Их диагностика методологически и деонтологически сложна. По мнению …

Anti-cancer drugs are chemotherapeutic agents that are designed to kill or reduce
proliferating cells. Often times, they interfere directly or indirectly with the cell's …

Many anti-neoplastic drugs are used globally during chemotherapy in the treatment of
cancer. However, occupational exposure to anti-cancer drugs can represent a potential …

The majority of anticancer agents has in common DNA-damaging properties and affects not
only target-cells but also non-tumour cells. Its genotoxicity has been demonstrated in …

The continuous introduction of new antineoplastic drugs and their use as complex mixture
emphasize the need to carry out correct health risk assessment. The aim of this study was to …

Abstract Ciprofloxacin (CIP), tamoxifen (TAM) and cyclophosphamide (CP) which are often
used in anticancer treatment are released in hospital effluent and into the environment …

Many antineoplastic drugs used to treat cancer, particularly alkylating agents and
topoisomerase inhibitors, are known to induce genetic damage in patients. Elevated levels …

Objectives Exposure to antineoplastic drugs should be avoided due to the risk of getting
adverse health effects. Antineoplastic drugs such as cyclophosphamide (CP) and ifosfamide …