Antibiotic resistance has become a global public health priority. Polymyxins, a family of
cationic polypeptide antibiotics, act as a final line of refuge against severe infections by …

Polymyxins are important lipopeptide antibiotics that serve as the last-line defense against
multidrug-resistant (MDR) Gram-negative bacterial infections. Worryingly, the clinical utility …

Objectives The continuing rise in infections caused by multidrug-resistant (MDR) bacteria is
one of the most serious public-health issues in society today. Colistin is a last-resort …

Abstract Purpose of Review The polymyxins are one of the last line antimicrobial classes to
retain activity against multidrug-resistant Gram-negative bacilli. However, with the increased …

Colistin resistance by mobilisable mcr genes has been described in bacteria of food-animal
origin worldwide, which has raised public health concerns about its potential foodborne …

This study aimed to evaluate the antibacterial activity of nine boron derivatives against
biofilm-forming pathogenic bacteria. The effect of boron derivatives (CMB, calcium …

Polymyxins, a group of cationic antimicrobial polypeptides, act as a last-resort defense
against lethal infections by carbapenem-resistant Gram-negative pathogens. Recent …

We evaluate here the presence of the mcr-1-like and mcr-2 genes in Escherichia coli and
Salmonella spp. isolated from healthy food-producing animals at slaughter between 2002 …

Antimicrobial-resistant Klebsiella pneumoniae represent a global public health concern. K.
pneumoniae strains isolated during 2010 and 2014–2016 within a single hospital of Molise …

The recent discovery of the plasmid‐mediated mcr-1 gene conferring resistance to colistin is
of clinical concern. The worldwide screening of this resistance mechanism among samples …