Although clinical use of the auditory brainstem response (ABR) to detect retrocochlear
disorders has been largely replaced by imaging in recent years, the discovery of cochlear …

The Sense of Hearing is a highly accessible introduction to auditory perception, addressing
the fundamental aspects of hearing. This fourth edition has been revised to include up-to …

Significance: Noise-induced hearing loss (NIHL) is an important public health issue resulting
in decreased quality of life for affected individuals, and significant costs to employers and …

Audiometric testing in research and in clinical settings rarely considers frequencies above 8
kHz. However, the sensitivity of young healthy ears extends to 20 kHz, and there is …

Aging, noise exposure, and ototoxic medications lead to cochlear synapse loss in animal
models. As cochlear function is highly conserved across mammalian species, synaptopathy …

Objectives: This study had two objectives: to examine associations between extended high-
frequency (EHF) thresholds, demographic factors (age, sex, race/ethnicity), risk factors …

Purpose: Animal models and human temporal bones indicate that noise exposure is a risk
factor for cochlear synaptopathy, a possible etiology of tinnitus. Veterans are exposed to …

It is well known that ageing and noise exposure are important causes of sensorineural
hearing loss, and can result in damage of the outer hair cells or other structures of the inner …

Age-related cochlear synaptopathy (CS) has been shown to occur in rodents with minimal
noise exposure, and has been hypothesized to play a crucial role in age-related hearing …

Noise exposure may damage the synapses that connect inner hair cells with auditory nerve
fibers, before outer hair cells are lost. In humans, this cochlear synaptopathy (CS) is thought …