Metabolomics in cancer research and emerging applications in clinical oncology

DR Schmidt, R Patel, DG Kirsch… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Guide to metabolomics analysis: a bioinformatics workflow

Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

Untargeted metabolomics analysis of esophageal squamous cell cancer progression

T Yang, R Hui, J Nouws, M Sauler, T Zeng… - Journal of translational …, 2022 - Springer
Abstract 90% of esophageal cancer are esophageal squamous cell carcinoma (ESCC) and
ESCC has a very poor prognosis and high mortality. Nevertheless, the key metabolic …

Metabolic phenotype of bladder cancer

F Massari, C Ciccarese, M Santoni, R Iacovelli… - Cancer treatment …, 2016 - Elsevier
Metabolism of bladder cancer represents a key issue for cancer research. Several metabolic
altered pathways are involved in bladder tumorigenesis, representing therefore interesting …

Artificially intelligent olfaction for fast and noninvasive diagnosis of bladder cancer from urine

Y Jian, N Zhang, T Liu, Y Zhu, D Wang, H Dong… - ACS …, 2022 - ACS Publications
Globally, bladder cancer (BLC) is one of the most common cancers and has a high
recurrence and mortality rate. Current clinical diagnostic approaches are either invasive or …

Cancer metabolomic markers in urine: evidence, techniques and recommendations

SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …

Emerging field of metabolomics: big promise for cancer biomarker identification and drug discovery

S Patel, S Ahmed - Journal of pharmaceutical and biomedical analysis, 2015 - Elsevier
Most cancers are lethal and metabolic alterations are considered a hallmark of this deadly
disease. Genomics and proteomics have contributed vastly to understand cancer biology …

Comprehensive targeted metabolomic assay for urine analysis

J Zheng, L Zhang, M Johnson, R Mandal… - Analytical …, 2020 - ACS Publications
Among all the human biological fluids used for disease biomarker discovery or clinical
chemistry, urine stands out. It can be collected easily and noninvasively, it is readily …

A review of validated biomarkers obtained through metabolomics

Á López-López, Á López-Gonzálvez… - Expert review of …, 2018 - Taylor & Francis
Introduction: Studying changes in the whole set of small molecules, final products of
biochemical reactions in living systems or metabolites, is extremely appealing because they …

[HTML][HTML] Effects of exposure to water disinfection by-products in a swimming pool: a metabolome-wide association study

K Van Veldhoven, P Keski-Rahkonen… - Environment …, 2018 - Elsevier
Background Exposure to disinfection by-products (DBPs) in drinking water and chlorinated
swimming pools are associated with adverse health outcomes, but biological mechanisms …