Understanding the bone in cancer metastasis
J Fornetti, AL Welm, SA Stewart - Journal of Bone and Mineral …, 2018 - academic.oup.com
The bone is the third most common site of metastasis for a wide range of solid tumors
including lung, breast, prostate, colorectal, thyroid, gynecologic, and melanoma, with 70% of …
including lung, breast, prostate, colorectal, thyroid, gynecologic, and melanoma, with 70% of …
Current concepts in bone metastasis, contemporary therapeutic strategies and ongoing clinical trials
Background Elucidation of mechanisms regulating bone metastasis has progressed
significantly in recent years and this has translated to many new therapeutic options for …
significantly in recent years and this has translated to many new therapeutic options for …
[HTML][HTML] Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Bone metastases are devastating complications of cancer. They are particularly common in
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …
A vertebral skeletal stem cell lineage driving metastasis
J Sun, L Hu, S Bok, AR Yallowitz, M Cung… - Nature, 2023 - nature.com
Vertebral bone is subject to a distinct set of disease processes from long bones, including a
much higher rate of solid tumour metastases,,–. The basis for this distinct biology of vertebral …
much higher rate of solid tumour metastases,,–. The basis for this distinct biology of vertebral …
Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial staging of …
NM Bruckmann, J Kirchner, L Umutlu, WP Fendler… - European …, 2021 - Springer
Objectives To compare the diagnostic performance of [18F] FDG PET/MRI, MRI, CT, and
bone scintigraphy for the detection of bone metastases in the initial staging of primary breast …
bone scintigraphy for the detection of bone metastases in the initial staging of primary breast …
Deep convolutional neural network-based segmentation and classification of difficult to define metastatic spinal lesions in 3D CT data
J Chmelik, R Jakubicek, P Walek, J Jan… - Medical image …, 2018 - Elsevier
This paper aims to address the segmentation and classification of lytic and sclerotic
metastatic lesions that are difficult to define by using spinal 3D Computed Tomography (CT) …
metastatic lesions that are difficult to define by using spinal 3D Computed Tomography (CT) …
Deep learning–based algorithm improved radiologists' performance in bone metastases detection on CT
Objectives To develop and evaluate a deep learning–based algorithm (DLA) for automatic
detection of bone metastases on CT. Methods This retrospective study included CT scans …
detection of bone metastases on CT. Methods This retrospective study included CT scans …
Revisiting the vertebral venous plexus–a comprehensive review of the literature
K Carpenter, T Decater, J Iwanaga, CM Maulucci… - World neurosurgery, 2021 - Elsevier
The venous drainage of the vertebral and paravertebral regions is important for a better
understanding of hematogenous disease spread. Moreover, the spine surgeon must be well …
understanding of hematogenous disease spread. Moreover, the spine surgeon must be well …
Gender-and age-associated differences in bone marrow adipose tissue and bone marrow fat unsaturation throughout the skeleton, quantified using chemical shift …
KM Beekman, M Regenboog, AJ Nederveen… - Frontiers in …, 2022 - frontiersin.org
Bone marrow adipose tissue (BMAT) is a dynamic tissue which is associated with
osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to …
osteoporosis, bone metastasis, and primary bone tumors. The aim of this study is to …
Total-body 68Ga-PSMA-11 PET/CT for bone metastasis detection in prostate cancer patients: Potential impact on bone scan guidelines
KL Pomykala, J Czernin, TR Grogan… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Our purpose was to determine the relationship between serum prostate-specific antigen
(PSA) level categories (< 5, 5–10, 10–20, and> 20 ng/mL) and the incidence of bone …
(PSA) level categories (< 5, 5–10, 10–20, and> 20 ng/mL) and the incidence of bone …