The multifaceted role of autophagy in cancer
RC Russell, KL Guan - The EMBO journal, 2022 - embopress.org
Autophagy is a cellular degradative pathway that plays diverse roles in maintaining cellular
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …
homeostasis. Cellular stress caused by starvation, organelle damage, or proteotoxic …
Role of mitochondrial quality surveillance in myocardial infarction: from bench to bedside
Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
Mitophagy in degenerative joint diseases
K Sun, X Jing, J Guo, X Yao, F Guo - Autophagy, 2021 - Taylor & Francis
Mitochondrial dysfunction is involved in aging and multiple degenerative diseases, including
intervertebral disc degeneration (IVDD) and osteoarthritis (OA). Thus, the maintenance of …
intervertebral disc degeneration (IVDD) and osteoarthritis (OA). Thus, the maintenance of …
Cellular and molecular differences between HFpEF and HFrEF: a step ahead in an improved pathological understanding
Heart failure (HF) is the most rapidly growing cardiovascular health burden worldwide. HF
can be classified into three groups based on the percentage of the ejection fraction (EF) …
can be classified into three groups based on the percentage of the ejection fraction (EF) …
Beclin-1-dependent autophagy protects the heart during sepsis
Background: Cardiac dysfunction is a major component of sepsis-induced multiorgan failure
in critical care units. Changes in cardiac autophagy and its role during sepsis pathogenesis …
in critical care units. Changes in cardiac autophagy and its role during sepsis pathogenesis …
Mitophagy in cancer: a tale of adaptation
M Vara-Perez, B Felipe-Abrio, P Agostinis - Cells, 2019 - mdpi.com
In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …
Human umbilical cord mesenchymal stem cell‐derived exosomes attenuate oxygen‐glucose deprivation/reperfusion‐induced microglial pyroptosis by promoting …
Z Hu, Y Yuan, X Zhang, Y Lu, N Dong… - Oxidative medicine …, 2021 - Wiley Online Library
Background. Mesenchymal stem cell‐derived exosomes (MSC‐exos) have been recognized
as a promising therapeutic strategy for neonatal hypoxic‐ischemic brain damage (HIBD) …
as a promising therapeutic strategy for neonatal hypoxic‐ischemic brain damage (HIBD) …
The role of mitochondrial dynamics in cardiovascular diseases
M Forte, L Schirone, P Ameri, C Basso… - British journal of …, 2021 - Wiley Online Library
The process of mitochondrial dynamics is emerging as a core player in cardiovascular
homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission …
homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission …
Mitochondria and inflammatory bowel diseases: toward a stratified therapeutic intervention
G Ho, AL Theiss - Annual review of physiology, 2022 - annualreviews.org
Mitochondria serve numerous critical cellular functions, rapidly responding to extracellular
stimuli and cellular demands while dynamically communicating with other organelles …
stimuli and cellular demands while dynamically communicating with other organelles …
SERCA control of cell death and survival
ER Chemaly, L Troncone, D Lebeche - Cell calcium, 2018 - Elsevier
Abstract Intracellular calcium (Ca 2+) is a critical coordinator of various aspects of cellular
physiology. It is increasingly apparent that changes in cellular Ca 2+ dynamics contribute to …
physiology. It is increasingly apparent that changes in cellular Ca 2+ dynamics contribute to …