Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress
S Rahman, S Mathew, P Nair, WS Ramadan… - …, 2021 - Springer
Berries are natural sources of anthocyanins, especially cyanidin-3-glucoside (C3G), and
exhibit significant antioxidant, antidiabetic, anti-inflammatory, and cytoprotective effects …
exhibit significant antioxidant, antidiabetic, anti-inflammatory, and cytoprotective effects …
Role of dietary antioxidants in p53‐mediated cancer chemoprevention and tumor suppression
JPJ Merlin, HPV Rupasinghe… - … Medicine and Cellular …, 2021 - Wiley Online Library
Cancer arises through a complex interplay between genetic, behavioral, metabolic, and
environmental factors that combined trigger cellular changes that over time promote …
environmental factors that combined trigger cellular changes that over time promote …
Current methodologies to refine bioavailability, delivery, and therapeutic efficacy of plant flavonoids in cancer treatment
CG Vazhappilly, M Amararathna, AC Cyril… - The Journal of …, 2021 - Elsevier
Over the last two decades, several advancements have been made to improve the
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …
therapeutic efficacy of plant flavonoids, especially in cancer treatment. Factors such as low …
Biomedical properties of propolis on diverse chronic diseases and its potential applications and health benefits
N Rivera-Yañez, CR Rivera-Yañez, G Pozo-Molina… - Nutrients, 2020 - mdpi.com
The use of alternative medicine products has increased tremendously in recent decades
and it is estimated that approximately 80% of patients globally depend on them for some part …
and it is estimated that approximately 80% of patients globally depend on them for some part …
p53: from fundamental biology to clinical applications in cancer
M Capuozzo, M Santorsola, M Bocchetti, F Perri… - Biology, 2022 - mdpi.com
Simple Summary p53 tumour suppressor gene is the most altered in cancer. Several
decades of research have established that it is of pivotal importance in prompting neoplastic …
decades of research have established that it is of pivotal importance in prompting neoplastic …
Bcl-2 modulation in p53 signaling pathway by flavonoids: A potential strategy towards the treatment of cancer
Cancer is a major cause of death, affecting human life in both developed and developing
countries. Numerous antitumor agents exist but their toxicity and low efficacy limits their …
countries. Numerous antitumor agents exist but their toxicity and low efficacy limits their …
Dietary aflatoxin B1 and antimalarial—a lumefantrine/artesunate—therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms
We investigated the impact of Coartem™(COA) and aflatoxin B1 (AFB1) on rats'
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …
hypothalamus, epididymis, and testis. Male rats were randomly grouped (n= 5 rats) and …
Potential protective effects of chrysin against immunotoxicity induced by diazinon
Acute intoxication with diazinon (DZN) as a pesticide causes mortality and morbidity
annually. This study shows the impact of sub-acute toxicity of DZN 20 mg/kg and the …
annually. This study shows the impact of sub-acute toxicity of DZN 20 mg/kg and the …
Vitamin-containing antioxidant formulation reduces carcinogen-induced DNA damage through ATR/Chk1 signaling in bronchial epithelial cells in vitro
Lung cancer has the highest mortality rate worldwide and is often diagnosed at late stages,
requiring genotoxic chemotherapy with significant side effects. Cancer prevention has …
requiring genotoxic chemotherapy with significant side effects. Cancer prevention has …
A dietary antioxidant formulation ameliorates DNA damage caused by γ-irradiation in normal human bronchial epithelial cells in vitro
Antioxidants can be used as radioprotectants to reduce DNA damage due to exposure to
radiation that could result in malignancies, including lung cancer. Mortality rates are …
radiation that could result in malignancies, including lung cancer. Mortality rates are …