Wilson's disease (WD) is characterised by a deleterious accumulation of copper in the liver
and brain. It is one of those rare genetic disorders that benefits from effective and lifelong …

Background Wilson disease (WD) is an inherited neurometabolic disorder that results in
excessive copper deposition in the liver and the brain, affecting children and young adults …

Copper is an essential metal required for many metalloproteins' function. A fraction of dietary
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …

Background: Clinical presentations of Wilson's disease (WD) in childhood ranges from
asymptomatic liver disease to cirrhosis or acute liver failure, whereas neurological and …

Clinical practice guidelines for Wilson's disease (WD) have been published by the American
Association for the Study of Liver Diseases and European Association for the Study of the …

Wilson's disease (WD) is an inherited metabolic disorder related to disturbances of copper
metabolism, and predominantly presents with liver and neuropsychiatric symptoms. In most …

Wilson disease is an autosomal-recessive disorder originating from a genetic defect in the
copper-transporting ATPase ATP7B that is required for biliary copper secretion and loading …

Wilson's disease (WD), albeit relatively rare, is an important genetic metabolic disease
because of highly effective therapies that can be lifesaving. It is a great imitator and requires …

Wilson disease (WD) is a rare, recessively inherited disorder of copper metabolism mainly
affecting liver and brain. In childhood, it is known to have a predominant hepatic phenotype …

Wilson's disease (WD) is a rare condition caused by copper accumulation primarily in the
liver and secondly in other organs, such as the central nervous system. It is a hereditary …