In IgA nephropathy (IgAN), there is dysregulation of the IgA response to a wide range of
antigens. The dysregulation promotes synthesis of polymeric IgA1 (pIgA1) with …

Despite the success of the campaigns to reduce the risk of sudden infant death syndrome
(SIDS), it still remains the major cause of postneonatal mortality. The incidence of SIDS is …

Currently, there is much interest in the genetic basis for diseases or disease manifestations
and, in particular, in whether they are related to cytokine gene polymorphisms. It has …

The North American Pediatric Renal Transplant Cooperative Study has collected clinical
information on children undergoing a renal transplantation since 1987. This cooperative …

The Diversity and Minority Affairs Committee of the American Society of Transplantation
(AST) convened a symposium to examine organ transplantation in underserved and minority …

Background. Allograft failure in African-Americans remains higher than in Caucasians.
Single nucleotide polymorphisms (SNPs) have been associated with altered allograft …

Background. Pretransplantation identification of patients at an increased risk for adverse
events would allow more individualized treatment strategies possibly improving long-term …

BACKGROUND/AIMS: The aim of this study was to assess whether genetic polymorphism of
three important candidate cytokine genes, IL-10 (− 1082G/A,− 819C/T, and− 592C/A), IL-4 …

Background. T-cell activation and regulation are under genetic control and vary between
individuals. However, the influence of functional immune response gene polymorphisms on …

BACKGROUND: Asthma is a complex disease characterized by sex-specific differences in
incidence, prevalence, and severity, but little is known about the molecular basis of these …