Background: The management of acute and chronic pain for individuals living with sickle cell
disease (SCD) is a clinical challenge. This reflects the paucity of clinical SCD pain research …

Mental disorders frequently begin in childhood or adolescence. Psychotropic medications
have various indications for the treatment of mental disorders in this age group and are used …

Anxiety disorders are among the most common psychiatric disorders in children and
adolescents. As reviewed in this guideline, both cognitive-behavioral therapy (CBT) and …

Depression in Adolescents Depression in adolescents is increasing at a greater rate than in
adults. Change in appetite, loss of energy, and insomnia may be more apparent than mood …

Depression in youth is prevalent and disabling and tends to presage a chronic and recurrent
course of illness and impairment in adulthood. Clinical trial research in youth depression …

The number of adolescent deaths that result from suicide in the United States had been
increasing dramatically during recent decades until 1990, when it began to decrease …

Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …

Objective To enhance the quality of care and clinical outcomes for children and adolescents
with major depressive disorder (MDD) and persistent depressive disorder (PDD). The aims …

Self-harm and suicide are major public health problems in adolescents, with rates of self-
harm being high in the teenage years and suicide being the second most common cause of …

Unipolar depressive disorder in adolescence is common worldwide but often unrecognised.
The incidence, notably in girls, rises sharply after puberty and, by the end of adolescence …