In 2015, approximately half a billion people had disabling hearing loss, about 6· 8% of the
world's population. These numbers are substantially higher than estimates published before …

Cochlea-Implantate sind elektronische Reizprothesen zum funktionellen Ersatz des
Innenohrs. Aufgrund der rasanten technischen Entwicklung und den dadurch erzielten …

At any age, disabling hearing impairment has a profound impact on interpersonal
communication, psychosocial well-being, quality of life and economic independence …

Progress in biomedical technology (cochlear, vestibular, and retinal implants) has led to
remarkable success in neurosensory restoration, particularly in the auditory system …

Autosomal recessive genetic forms (DFNB) account for most cases of profound congenital
deafness. Adeno-associated virus (AAV)-based gene therapy is a promising therapeutic …

Deafness is a heterogeneous condition with far-reaching effects on social, emotional, and
cognitive development. Onset before language has been established happens in about …

Cortical development is dependent on stimulus-driven learning. The absence of sensory
input from birth, as occurs in congenital deafness, affects normal growth and connectivity …

Mice lacking the vesicular glutamate transporter-3 (VGLUT3) are congenitally deaf due to
loss of glutamate release at the inner hair cell afferent synapse. Cochlear delivery of …

The article reviews evidence for sensitive periods in the sensory systems and considers their
neuronal mechanisms from the viewpoint of the system's neuroscience. It reviews the …

The modern cochlear implant (CI) is the most successful neural prosthesis developed to
date. CIs provide hearing to the profoundly hearing impaired and allow the acquisition of …