Role of the gut microbiota in regulating non-alcoholic fatty liver disease in children and adolescents

D Tokuhara - Frontiers in Nutrition, 2021 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
in children and adolescents. Although obesity is the leading cause of NAFLD, the etiologies …

Inflammation and oxidative stress induced by obesity, gestational diabetes, and preeclampsia in pregnancy: role of high-density lipoproteins as vectors for bioactive …

AS Jiménez-Osorio, E Carreón-Torres, E Correa-Solís… - Antioxidants, 2023 - mdpi.com
Inflammation and oxidative stress are essential components in a myriad of pathogenic
entities that lead to metabolic and chronic diseases. Moreover, inflammation in its different …

Epigenetic biomarkers for the diagnosis and treatment of liver disease

M Arechederra, M Recalde, M Gárate-Rascón… - Cancers, 2021 - mdpi.com
Simple Summary Cellular identity and function depends on the correct and specific
expression of genetic information. Different epigenetic mechanisms including DNA …

[PDF][PDF] Developmental programming of NAFLD by parental obesity

MD Thompson - Hepatology Communications, 2020 - Wiley Online Library
The surge of obesity across generations has become an increasingly relevant issue, with
consequences for associated comorbidities in offspring. Data from longitudinal birth cohort …

Preconception diet interventions in obese outbred mice and the impact on female offspring metabolic health and oocyte quality

B Meulders, WFA Marei, I Xhonneux, L Loier… - International journal of …, 2024 - mdpi.com
Obese individuals often suffer from metabolic health disorders and reduced oocyte quality.
Preconception diet interventions in obese outbred mice restore metabolic health and oocyte …

Effect of gestational fish oil supplementation on liver metabolism and mitochondria of male and female rat offspring programmed by maternal high‐fat diet

JGO Neto, J Woyames, CBV Andrade… - Molecular nutrition & …, 2023 - Wiley Online Library
Scope Perinatal maternal moderately high‐fat diet (mHFD) is associated with obesity and
fatty liver disease in offspring, and maternal fish oil (FO: n‐3 PUFA source) supplementation …

[HTML][HTML] Pregnancy and metabolic-associated fatty liver disease: a clinical update

S Fouda, MM Vennikandam… - Journal of clinical and …, 2022 - ncbi.nlm.nih.gov
The intricate relationship between metabolic-associated fatty liver disease (MAFLD) and
maternal complications has rapidly become a significant health threat in pregnant women …

Maternal high‐fat diet disrupted one‐carbon metabolism in offspring, contributing to nonalcoholic fatty liver disease

H Peng, H Xu, J Wu, J Li, Y Zhou, Z Ding… - Liver …, 2021 - Wiley Online Library
Abstract Background & Aims Pregnant women may transmit their metabolic phenotypes to
their offspring, enhancing the risk for nonalcoholic fatty liver disease (NAFLD); however, the …

Maternal exercise mediates hepatic metabolic programming via activation of AMPK-PGC1α axis in the offspring of obese mothers

P Kasper, S Breuer, T Hoffmann, C Vohlen… - Cells, 2021 - mdpi.com
Maternal obesity is associated with an increased risk of hepatic metabolic dysfunction for
both mother and offspring and targeted interventions to address this growing metabolic …

Maternal weight management to prevent the developmental programming of MAFLD in offspring of obese mothers

AR Purcell, SJ Glastras - Nutrients, 2023 - mdpi.com
The global surge of obesity amongst women of reproductive age has raised concerns
surrounding the health consequences for their offspring as there is a formidable link …