Metal–Organic Frameworks for Nerve Repair and Neural Stem Cell Therapy

L Meng, N Ren, M Dong, S Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Recently, neurological disorders have led to a growing global burden of fatalities and
disabilities. The limited capacity for natural self‐regeneration poses a significant challenge …

Engineering a wirelessly self-powered and electroconductive scaffold to promote peripheral nerve regeneration

Y Yang, X Yin, H Wang, W Qiu, L Li, F Li, Y Shan… - Nano Energy, 2023 - Elsevier
Electroactive biomaterials have been shown useful for the repair of injured peripheral nerve.
While for conventional conductive conduits, outer electrical stimulation device is …

Bioelectronics for electrical stimulation: materials, devices and biomedical applications

Y Huang, K Yao, Q Zhang, X Huang, Z Chen… - Chemical Society …, 2024 - pubs.rsc.org
Bioelectronics is a hot research topic, yet an important tool, as it facilitates the creation of
advanced medical devices that interact with biological systems to effectively diagnose …

Enhanced M2 polarization of oriented macrophages on the P (Vdf-Trfe) film by coupling with electrical stimulation

J Gu, C Wu, X He, X Chen, L Dong… - ACS Biomaterials …, 2023 - ACS Publications
Electrical stimulation (ES) has been considered a promising strategy in regulating
intracellular communication, membrane depolarization, ion transport, etc. Meanwhile, cell …

High-efficiency brain-targeted intranasal delivery of BDNF mediated by engineered exosomes to promote remyelination

Y Zhai, Q Wang, Z Zhu, Y Hao, F Han, J Hong… - Biomaterials …, 2022 - pubs.rsc.org
The regeneration of myelin sheaths is the ultimate goal of the treatment of demyelination
disease, including multiple sclerosis (MS). However, current drugs for MS mainly target the …

Wireless electromagnetic neural stimulation patch with anisotropic guidance

BN Jensen, Y Wang, A Le Friec, S Nabavi… - npj Flexible …, 2023 - nature.com
The human body is limited in healing neurological damage caused by diseases or traumatic
injuries. Bioelectricity is a quintessential characteristic of neural tissue and has a crucial role …

Antioxidant MnO2 nanozymes-encapsulated hydrogel synergistically regulate the spinal ROS microenvironment and promote spinal cord repair

R Fan, D Chuan, Z Liu, H Chen, C Chen, G Guo… - Chemical Engineering …, 2023 - Elsevier
Traumatic spinal cord injury (SCI) usually leads to neuronal death and axon destruction,
resulting in long-term dysfunction, permanent functional impairment, significant caregiving …

Highly specific differentiation of MSCs into neurons directed by local electrical stimuli triggered wirelessly by electromagnetic induction nanogenerator

L Liang, C Liu, P Cai, S Han, R Zhang, N Ren, J Wang… - Nano Energy, 2022 - Elsevier
Transdifferentiation of mesenchymal stem cells (MSCs) into neurons provides a practical
way for neurodegenerative diseases as alternatives to neural stem cells, but is confronted …

Crocetin regulates functions of neural stem cells to generate new neurons for cerebral ischemia recovery

Z Liu, Z Wang, Z Zhu, J Hong, L Cui… - Advanced …, 2023 - Wiley Online Library
Many neurons undergo apoptosis after ischemic stroke. In the brain, neurogenesis has the
potential for neuronal replacement and can be activated by external conditions to repair the …

Gold Nanostrip Array‐Mediated Wireless Electrical Stimulation for Accelerating Functional Neuronal Differentiation

H Yang, Y Su, Z Sun, B Ma, F Liu, Y Kong… - Advanced …, 2022 - Wiley Online Library
Neural stem cell (NSC)‐based therapy holds great promise for the treatment of
neurodegenerative diseases. Presently, however, it is hindered by poor functional neuronal …