DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation
Y An, X Zhao, Z Zhang, Z Xia, M Yang, L Ma… - Nature …, 2023 - nature.com
Plasma cell-free DNA (cfDNA) are small molecules generated through a non-random
fragmentation procedure. Despite commendable translational values in cancer liquid biopsy …
fragmentation procedure. Despite commendable translational values in cancer liquid biopsy …
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments
M Begnis, J Duc, S Offner, D Grun, S Sheppard… - Science …, 2024 - science.org
Long known as the site of ribosome biogenesis, the nucleolus is increasingly recognized for
its role in shaping three-dimensional (3D) genome organization. Still, the mechanisms …
its role in shaping three-dimensional (3D) genome organization. Still, the mechanisms …
[HTML][HTML] Cell-free DNA end characteristics enable accurate and sensitive cancer diagnosis
J Ju, X Zhao, Y An, M Yang, Z Zhang, X Liu, D Hu… - Cell Reports …, 2024 - cell.com
The fragmentation patterns of cell-free DNA (cfDNA) in plasma can potentially be utilized as
diagnostic biomarkers in liquid biopsy. However, our knowledge of this biological process …
diagnostic biomarkers in liquid biopsy. However, our knowledge of this biological process …
The genomic mosaic of mitochondrial dysfunction: Decoding nuclear and mitochondrial epigenetic contributions to maternally inherited diabetes and deafness …
L Donato, C Scimone, S Alibrandi, M Vadalà… - Heliyon, 2024 - cell.com
Aims Maternally inherited diabetes and deafness (MIDD) is a complex disorder
characterized by multiorgan clinical manifestations, including diabetes, hearing loss, and …
characterized by multiorgan clinical manifestations, including diabetes, hearing loss, and …
DNA Methylation Data Analysis Using Msuite
X Liu, P Yuan, K Sun - Computational Epigenomics and …, 2023 - Springer
DNA methylation is a widespread epigenetic modification responsible for many biological
regulation pathways. The development of various powerful biochemical assays, including …
regulation pathways. The development of various powerful biochemical assays, including …