Lactate acidosis and simultaneous recruitment of TGF-β leads to alter plasticity of hypoxic cancer cells in tumor microenvironment
Lactate acidosis is often observed in the tumor microenvironment (TME) of solid tumors. This
is because glucose breaks down quickly via glycolysis, causing lactate acidity. Lactate is …
is because glucose breaks down quickly via glycolysis, causing lactate acidity. Lactate is …
Untangling cell tracks: Quantifying cell migration by time lapse image data analysis
CM Svensson, A Medyukhina, I Belyaev… - Cytometry Part …, 2018 - Wiley Online Library
Automated microscopy has given researchers access to great amounts of live cell imaging
data from in vitro and in vivo experiments. Much focus has been put on extracting cell tracks …
data from in vitro and in vivo experiments. Much focus has been put on extracting cell tracks …
Cell-membrane-coated and cell-penetrating peptide-conjugated trimagnetic nanoparticles for targeted magnetic hyperthermia of prostate cancer cells
Prostate malignancy represents the second leading cause of cancer-specific death among
the male population worldwide. Herein, enhanced intracellular magnetic fluid hyperthermia …
the male population worldwide. Herein, enhanced intracellular magnetic fluid hyperthermia …
Unjamming and collective migration in MCF10A breast cancer cell lines
JH Kim, AF Pegoraro, A Das, SA Koehler… - Biochemical and …, 2020 - Elsevier
Each cell comprising an intact, healthy, confluent epithelial layer ordinarily remains
sedentary, firmly adherent to and caged by its neighbors, and thus defines an elemental …
sedentary, firmly adherent to and caged by its neighbors, and thus defines an elemental …
Non-Gaussianity, population heterogeneity, and transient superdiffusion in the spreading dynamics of amoeboid cells
What is the underlying diffusion process governing the spreading dynamics and search
strategies employed by amoeboid cells? Based on the statistical analysis of experimental …
strategies employed by amoeboid cells? Based on the statistical analysis of experimental …
Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma
R Huang, S Li, C Tian, P Zhou, H Zhao, W Xie… - British Journal of …, 2022 - nature.com
Background The transient receptor potential vanilloid receptor 2 (TRPV2) has been found to
participate in the pathogenesis of various types of cancers, however, its role (s) in the …
participate in the pathogenesis of various types of cancers, however, its role (s) in the …
Fighting carcinogenesis with plant metabolites by weakening proliferative signaling and disabling replicative immortality networks of rapidly dividing and invading …
Background: Cancer, an uncontrolled multistage disease causing swift division of cells, is a
leading disease with the highest mortality rate. Cellular heterogeneity, evading growth …
leading disease with the highest mortality rate. Cellular heterogeneity, evading growth …
Recurrent activations of transient receptor potential vanilloid‐1 and vanilloid‐4 promote cellular proliferation and migration in esophageal squamous cell carcinoma …
R Huang, F Wang, Y Yang, W Ma, Z Lin… - FEBS Open …, 2019 - Wiley Online Library
Some members of the transient receptor potential vanilloid (TRPV) subfamily of cation
channels are thermosensitive. Earlier studies have revealed the distribution and functions of …
channels are thermosensitive. Earlier studies have revealed the distribution and functions of …
Relationship between miR-143/145 cluster variations and cancer risk: proof from a Meta-analysis
Recent studies have suggested that single-nucleotide polymorphisms (SNPs) located in the
miR-143/145 cluster might be linked to cancer risk. In this meta-analysis association study …
miR-143/145 cluster might be linked to cancer risk. In this meta-analysis association study …
Active matter in a viscoelastic environment
Active matter systems such as eukaryotic cells and bacteria continuously transform chemical
energy to motion. Hence living systems exert active stresses on the complex environments …
energy to motion. Hence living systems exert active stresses on the complex environments …