[HTML][HTML] A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - ACS biomaterials …, 2020 - ACS Publications
Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Electrochemical sensing directions for next-generation healthcare: trends, challenges, and frontiers

JF Hernández-Rodríguez, D Rojas… - Analytical …, 2020 - ACS Publications
Unfortunately, last year we have witnessed one of the worst global health crises in recent
history. SARS-COV-2 pandemic outbreak has revealed that global healthcare systems were …

[HTML][HTML] Design and fabrication of organ-on-chips: promises and challenges

A Tajeddin, N Mustafaoglu - Micromachines, 2021 - mdpi.com
The advent of the miniaturization approach has influenced the research trends in almost all
disciplines. Bioengineering is one of the fields benefiting from the new possibilities of …

Advanced materials and sensors for microphysiological systems: focus on electronic and electrooptical interfaces

H Kavand, R Nasiri, A Herland - Advanced Materials, 2022 - Wiley Online Library
Advanced in vitro cell culture systems or microphysiological systems (MPSs), including
microfluidic organ‐on‐a‐chip (OoC), are breakthrough technologies in biomedicine. These …

Engineered biomimetic membranes for organ-on-a-chip

M Rahimnejad, F Rasouli, S Jahangiri… - ACS Biomaterials …, 2022 - ACS Publications
Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the
physiochemical environment of a specific organ in the body. Among various components of …

Membrane integration into PDMS-free microfluidic platforms for organ-on-chip and analytical chemistry applications

S Schneider, D Gruner, A Richter, P Loskill - Lab on a Chip, 2021 - pubs.rsc.org
Membranes play a crucial role in many microfluidic systems, enabling versatile applications
in highly diverse research fields. However, the tight and robust integration of membranes …

Integration of extracellular matrices into organ‐on‐chip systems

H Kutluk, EE Bastounis… - Advanced Healthcare …, 2023 - Wiley Online Library
The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

[HTML][HTML] Intestinal models for personalized medicine: from conventional models to microfluidic primary intestine-on-a-chip

XG Li, M Chen, S Zhao, X Wang - Stem Cell Reviews and Reports, 2021 - Springer
Intestinal dysfunction is frequently driven by abnormalities of specific genes, microbiota, or
microenvironmental factors, which usually differ across individuals, as do intestinal …